Anti Tubercular Drugs

Question 1

Classification of TB ? IRSPE😂

Answer 1

Classification
1. First-line antitubercular drugs (standard drugs): Isoniazid (H), rifampin
(R), pyrazinamide (Z), ethambutol (E), streptomycin (S)
2. Second-line antitubercular
drugs (reserve drugs): para-Aminosalicylic acid
(PAS), thiacetazone, cycloserine, ethionamide, kanamycin, capreomycin, amikacin, levofloxacin, moxifloxacin, ofloxacin, clarithromycin, rifabutin, rifapentine
Another form of classification is shown in Table 11.14.

Question 2

Prasad, 40-year-man weighing 60 kg suffering from chronic cough with expectoration and fever was diagnosed to have cavitary pulmonary tuberculosis.
(a) Classify the drugs used in the treatment of tuberculosis.
(b) Discuss in detail on the mechanism of action and adverse effects of first line antitubercular drugs.
(c) Add a note on the drug therapy of Multi Drug Resistant tuberculosis