Pentose Phosphate Pathway

Question 1

Purpose of PPPW

Answer 1

to produce high energy redox for pentose production (ribose), fats, cholesterol, and glutathionine

Question 2

Rate limiting step

Answer 2

initial step, Glucose-6-phosphate dehydrogenase conversion of glucose 6 phosphate into something else (dont owrry about it)

this is the oxidative phase

Question 3

The ultimate intermediate in the pentoss phosphate pathway is

Answer 3

ribulose-5-phosphate

Question 4

ribulose 5 phosphate does what

Answer 4

it can be used to make ribose-5-phosphate and nucleotide biosynthesis

Question 5

PPPW mode 1

Answer 5

much more ribose 5 phosphate required than NADPH

F6P and G3P used as substrates

no nadph produced

Question 6

PPPW mode 2

Answer 6

NADPH and ribose-5-phosphate needs are balanced

G6P used mostly

Question 7

PPPW mode 3

Answer 7

NADPH needed more than ribose 5 phosphate

2 NADPH produced

ribulose–>ribose–> G3P and F6P recycled

Question 8

PPPW mode 4

Answer 8

BOTH NADPH and ATP are required

Ribose converted into G3P after producing NADPH in order to produce pyruvate and ATP