penicillin

Question 1

penicillin G group

Answer 1

beta lactam antibiotics

Question 2

peniciilin MOA

Answer 2

interfere with the synthesis of bacterial cell wall

has bactericidal action

Question 3

penicillin uses

Answer 3

1. streptococcal infections such as pharyngitis, otitis media, scarlet fever, rheumatic fever
2. syphilis
3. ANUG
4. pneumonia, meningitis
5. prophylactic use in rheumatic fever, bacterial endocarditis

Question 4

penicillin A/E

Answer 4

1. n/v
2. pain at im injection site
3. thrombophlebitis at injection site
4. hypersensitivity-rash, itching, urticaria, fever, wheezing
5. large dose: mental confusion, muscular twitching, convulsion

Question 5

Ampicillin group

Answer 5

extended spectrum peniciilin

Question 6

ampicillin MOA

Answer 6

interfere with the synthesis of bacterial cell wall
has bactericidal action
active against all organisms sensitive to penicillin G

Question 7

ampicillin uses

Answer 7

1. UTI
2. respiratory tract infection such as bronchitis, sinusitis, otitis media
3. meningitis
4. gonorrhea
5. cholecystitis
6. subacute bacterial endocarditis
7. h pylori eradication

Question 8

ampicillin A/E

Answer 8

• diarrhea
• anaphylaxis, rashes
• n/v
• seizures

Question 9

piperacillin group

Answer 9

extended spectrum penicillin(ureidopenicillin)

Question 10

piperacillin MOA

Answer 10

interfere with the synthesis of bacterial cell wall
has bactericidal action
active against all organisms sensitive to penicillin G
commonly used with tazobactam as beta lactamase inhibitor

Question 11

piperacillin uses

Answer 11

• strong action against pseudomonas
• hospital acquired infection
• treating serious gram negative infections in neutropenic/immunocompromised patients

Question 12

piperacillin A/E

Answer 12

• diarrhea/constipation
• n/v
• headache,insomnia
• SJS
• clostridium difficle associated diarrhea