gentamicin

Question 1

gentamicin group

Answer 1

• aminoglycoside

Question 2

gentamicin moa

Answer 2

• inhibits protein synthesis
• bactericidal action
• active mainly against gram negative bacilli
• synergistic activity with penicillin/ cephalosporin

Question 3

gentamicin uses

Answer 3

• respiratory infection in critically ill patients (anticancer drugs, high dose corticosteroids, AIDS, neutropenic)
• postop pneumonia
• added to peritoneal diasylate to prevent/ prevetn peritonitis
• pseudomonas, proteus, klebsiella infection - burns, UTI, pneumonia, lung abscess, osteomyelitis, middle ear infection
• sub acute bacterial endocarditis

Question 4

gentamicin A/E

Answer 4

• ototoxicity
• nephrotoxicity
• neuromuscular blockade