Peer 8 - systemic infectious disorders Flashcards
dx of amebiasis?
stool examination for cysts, antigen tests on stool, or serum serology
tx of amebiasis?
metronidazole + iodoquinol or paromomycin
defn of toxic shock syndrome?
fever, diffuse macular erythroderma, desquamation, hypotension, and
- vomiting/diarrhea, renal failure, elevated transaminases, thrombocytopenia, AMS
adult with previous tetanus shot needs what if presents with laceration/open wound?
tdap
tx of clostridial myonecrosis?
can be monotherapy:
imipenem-cilastatin, meropenem, ertapenem, zosyn
cause of clostridial myonecrosis?
post surgical or traumatic wounds, affects already infected or traumatized tissue
chickenpox rash?
vesicular eruption primarily on trunk with lesions in various stages of development?
smallpox rash?
synchronized vesicular eruption with highest concentration on face and limbs
sx of histoplasma?
erythema nodosum (painful red nodules on surfaces of anterior lower leg), pneumonia, and headache
definitive diagnosis of malaria?
blood smear
sx of malaria?
high fever, ill appearance, tachypnea, and tachycarida
tx of toxoplasmosis in AIDS patient with ring enhancing lesions?
pyrimethamine, and sulfadiazine plus folinic acid
sx of ehrlichiosis?
myalgias, malaise, headache, nausea, vomiting, anorexia, abd pain
- labs show leukopenia, thrombocytopenia, liver enzymes
late stage complications of lyme disease?
fever, adenopathy, annular lesions, bilateral facial palsy, cardiac abnormalities
- tertiary - chronic arthritis, myocarditis, subacute encephalopathy, axonal polyneuropathy
tx of choice for rocky mountain spotted fever?
doxy 100 mg BID for 7-10 days
side effect of efavirenz?
psychosis and depression
side effect of nevirapine?
hepatic failure
side effect of ritonavir?
metabolic syndrome and hyperlipidemia
side effect of indinavir?
nephrolithiasis
side effect of zidovudine, didanosine, lamivudine
lactic acidosis
azt - bone marrow suppression, macro anemia
roseola sx?
high spiking fevers, then nondescript rash
rubella sx?
rash moves head to toe with fever, and soft palate findings
measles sx?
koplik spots and rash spreads head to toe with confluence
tx of rocky mountain spotted fever in pediatric patients?
doxy
sx of rocky mountain spotted fever?
fever, myalgias, HA, abd pain, macular rash from extremities to torso
diagnostic test of choice for giardiasis?
stool antigen
tx of PCP (PNA)?
bactrim 21 days
tx of severe PCP? defn of severe PCP?
steroids
Pao2 less than 70, A-a gradient of 35 or more, oxygen saturation less than 92% on room air