Peer 8 - heme diseases

Question 1

low platelets, prolonged coag times, and low fibrinogen with elevated d-dimer?

Answer 1

DIC

Question 2

aplastic crisis in sickle cell?

Answer 2

retic count < 3%, should give packed rbc

Question 3

cause of anemia of patient taking nitrofurantoin?

Answer 3

oxidative stress caused by thalassemia

Question 4

tx of head injury with hemophilia a

Answer 4

factor 8 therapy to 100% activity

Question 5

formula for amount of factor to give?

Answer 5

kg x 0.5 x percentage change in factor (40%)

Question 6

tx of polycythemia?

Answer 6

phlebotomy and volume replacement with saline to reduce hct to less than 55%, with stroke low dose aspirin should be started