Peds

Question 1

Drugs with dec dosing in peds

Answer 1

Opioids

more TBW = higher Vd
Less muscle = inc duration
Dec hepatic function and GFR
Dec protein binding in neonates = higher free fraction

Question 2

Drugs needing higher doses in peds

Answer 2

Propofol
Thiopental
Sux
Hypnotics

Question 3

Rate of infusion of dextrose containing fluids in neonates

Answer 3

4-7mg/kg/min

10% dextrose = 100mg/ml

Question 4

Dose of epi for IV injection detection of local

Answer 4

0.5mcg/kg up to 15mcg

Positive test dose = inc T-wave amplitude by 25%

Question 5

Post- T and A hemorrhage timing

Answer 5

first 6 hours

Question 6

Congenital heart lesions requiring PGE1 infusion

Answer 6

Pulmonary or tricuspid atresia - where there is no other pulmonary blood flow

Question 7

Cause of hypoxemia and cardiovascular collapse with CDH

Answer 7

Pulmonary HTN and lung hypoplasia

- should be fixed before correction

Question 8

Management of HLHS hypotension and inc SpO2 following induction

Answer 8

Likely due to dec in PVR from high FiO2 and hyperventilation of mask induction.

Ductal dependent for systemic blood flow = balance pulmonary and systemic BF.

Dec MV, dec FiO2, fluid bolus,

Question 9

PFTs with scoliosis

Answer 9

Restrictive - proportionate dec in all volumes

Question 10

Ebstein’s anomaly

Answer 10

Septal and posterior leaflets of tricuspid valve positioned down into RV with long, redundant anterior leaflet.
RV hypoplastic