Blood

Question 1

Cryo contents

Answer 1

Fibrinogen
vWF
VIII
XIII

Question 2

Treatments for:
vWD type 1
vWD type 2

Answer 2

1 = desmopressin

2 = try desmopressin unless type 2b = vWF factor concentrate

Question 3

Calculate volume of blood to transfuse

Answer 3

Volume = (Hct-end - Hct-start) x EBV / 65

Question 4

When to use exchange transfusion

Answer 4

Acute chest syndrome

Question 5

Most common transfusion reaction

Answer 5

Febrile non-hemolytic

- donor leukocytes

Question 6

Coagulation factors downregulated in sepsis

Answer 6

Anti-coagulants

• thrombomodulin
• endothielan protein receptor C
• APC
• protein S

Question 7

Most number of uncross matched O- blood one can receive and go back to type specific

Answer 7

2

Anti-A and Anti-B in donor O- will lead to intravascular hemolysis of type specific blood.

More O- will just give hyperbilirubinemia

Question 8

Who needs washed RBCs

Answer 8

IgA deficiency - previous anaphylactic reaction to transfusion

Question 9

Indications for DDAVP

Answer 9

vWD
Hemophilia A
Uremia-induced platelet dysfunction