Pediatrics: School-Age Children Flashcards
Danger Signals! Kawasaki Disease/Syndrome
- Onset of high fever (up to 104.0º F) for ≥ 5 days
Presence of at least 4 of the following clinical signs:
- enlarged lymph nodes in neck
- bright-red rash (more obvious on groin area)
- bilateral conjunctivitis (dry, no discharge)
- oral mucosal changes (e.g., dry cracked lips, “strawberry tongue”)
- swollen hands/feet
After fever subsides, skin peels off hands and feet
Tx:
- high-dose aspirin
- IV gamma globulin
- ~75% of cases occur in children <5 yo
- resolves within 1-3 weeks
- may have serious sequelae: aortic dissection, dilation or aneurysms of coronary arteries, and hearing loss
- requires close follow-up w/ p[ediatric cardiologist for several years d/t effects may not be apparent until child is older (or an adult)
Danger Signals! Leukemia
- c/o extreme fatigue and weakness
- pale skin
- easy bruising
- may have petechial bleeding (pinpoint to small red spots)
- may have bleeding gums/nosebleeds
- some have bone/joint pain
- lymphadenopathy
- abdominal swelling
- Most common type of CA in children/adolescents
- most common type: ALL
Danger Signals! Acute Lymphocytic Leukemia (ALL)
- most common form of leukemia in childhood (75%)
- fast-growing CA of the lymphoblasts, which are immature lymphocytes
- peak occurrence at 2-4 years
- CBC will show very HIGH WBC (>50,000 cells/mm3)
- girls have higher chance of cure
- African Americans, Hispanic children tend to have lower cure rate compared to other races
Danger Signals! Acute Myelogenous Leukemia (AML)
- fast-growing CA of bone marrow, affecting immature or precursor blood cells such as myeloblasts (WBCs), monoblasts (macrophages, monocytes), erythroblasts (RBCs), megakaryoblasts (platelets)
- Children w/ Down syndrome who have AML tend to have better cure rates, esp; if child is <4 years
Danger Signals! Reye’s Syndrome
Clinical Staging: Mild to Moderate, Severe
- Hx of febrile viral illness (chickenpox, influenza) and aspirin or salicylate intake (e.g., Pepto-Bismol) in child
- Theoretical risk of Reye’s syndrome after varicella immunization
- Avoid using aspiring before, during, and after immunization
- Abrupt onset w/ quick progression
- death can occur within a few hrs to a few days
- mortality rate up to 52%
- Although most cases are in children, teenagers and adults may be diagnosed; disease is now rare
Mild to Moderate
* Stage 1
- Severe vomiting
- lethargic/sleepy
- elevated ALT and AST
- Stage 2
- deeply lethargic
- restless
- confused/delirious/combative
- hyperactive reflexes
- hyperventilation
- Stage 3
- obtunded or in light coma
- decorticate rigidity
Severe
* Stage 4
- Coma
- seizure
- decerebrate rigidity
- fixed pupils
- loss of reflexes
- Stage 5
- Seizures
- deep coma
- flaccid paralysis
- absent DTRs
- respiratory arrest
- death
Down Syndrome: Atlantoaxial Instability
- Up to 15% of Down Syndrome pts have atlantoaxial instability
- Medical clearance is recommended for some sports participation
- children/adolescents (or older) w/ Dwon syndrome who want to participate in sports sneed cervical spine x-rays (including lateral view)
- pts w/ atlantoxial instability are restricted from playing contact sports 9e.g., basketball, tackle football, soccer) and other high-risk activities (e.g., trampoline jumping)
- persons w/ Down syndrome w/out evidence of atlantoaxial instability may participate in low-impact sports and sports not requiring extreme balance
atlantoaxial instability
excessive mobility at the articulation of C1 and C2)
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Hypertrophic Cardiomyopathy
- Risk of sudden cardiac death w/ intense exercise
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Atlantoaxial instability (Down syndrome, juvenile RA)
- Instability b/w C1 and C2 can cause spinal cord compression
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Marfan syndrome
- Risk of aortic aneurysm and cardiac death
- lens eyes displacement
- joint hypermobility
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Ehlers-Danlos syndrome (Vascular form)
- risk of cerebral or cervical artery aneurysm
- spondylolisthesis
- joint hypermobility
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Acute rheumatic fever w/ carditis
- Worsens condition
- heart inflamed
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Mitral Valve prolapse, esp if significant MV pathology
- risk of sudden cardiac death
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Fever
- Risk of heart illness, hypotension, and ↑ cardiopulmonary effort
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Infectious diarrhea
- risk of dehydration and heat illness; contagious
Medical Conditions that May Disqualify Youth From Sports Participation + Rationale: Pink Eye
- contagious
Absence Seizures
- brief episodes during which child suddenly stops whatever they are doing and stares
- if in school, teacher may tell parent that child is daydreaming and inattentive
- common type of pediatric seizure
- AKA: petit mal seizure
First-line therapy: ethosuximide
→ Refer to pediatric neurologist
Still’s Murmur
- benign systolic murmur, described as having a vibratory or musical quality
- becomes louder in supine position or w/ fever
- minimal radiation
- Grade I/II intensity
- most common in school-age children
- usually resolves by adolescence
US Health Statistics: School-Age Children
Top Causes of Death: Age 5-9 years (Early school age)
- Malignant neoplasms
- MVA
- Congenital abnormalities