Pediatrics: Newborns and Infants Flashcards
Danger Signals: Failure to Thrive
Definition:
- weight for age falls below 3rd-5th percentile for gestation-corrected age and gender when plotted on appropriate growth chart (on more than 1 occasion)
- infants whose weight ↓ over ≥2 major percentile lines (90th, 75th, 50th, 25th, and 5th) = failure to thrive (FTT) ; ex: child at 50th percentile goes down to 5th percentile over a few months
- Use WHO growth chart until 2 yo, then CDC’s
In most cases in primary care, causes are usually:
- inadequate dietary intake
- diarrhea
- malabsorption (celiac, CF, food allergy)
- poor maternal bonding
- frequent infections
Danger Signals: Down Syndrome
- genetic defect caused by trisomy of chromosome 21 (3 copies instead of 2)
- Most common chromosomal ds
- avg lifespan is 60 yo
S/Sx
- round face that appears “flat” (↓ anterior-posterior diameter)
- upward-slanting eyes (palpebral fissures)
- low-set ears
- chronic open mouth d/t enlarged tongue (macroglossia)
- shorter neck
- short fingers
- small palms
- broad hand w/ transverse palmar crease (Simian crease)
NB:
- hypotonia
- poor Moro reflex
- Higher risk of intellectual disability
- congenital heart defects (50%)
- feeding difficulties
- congenital hearing loss
- thyroid disease
- cataracts
- sleep apnea
- early onset of Alzheimer’s ds (avg age 54 years)
Education:
- importance of cervical spine positioning
- monitor for myelopathic s/sx
- contact sports (football, soccer, gymnastics) may place higher risk of spinal cord injury
- avoid trampoline use unless under professional supervision
- Special Olympics requires specific screening for some sports
Danger Signals: Fetal Alcohol Syndrome
- AKA Fetal alcohol Spectrum Ds
Classic FAS facies:
- small head (microcephaly)
- shortened palpebral fissures (narrow eyes) w/ epicanthal folds
- flat nasal bridge
- thin upper lip w/ no vertical groove above upper lip (smooth philtrum)
- ears are underdeveloped
- can range from neurocognitive and behavioral problems (e.g., ADD to more severe intellectual disabilities)
- NO safe dose or time for alcohol during pregnancy
- Alcohol adversely affects CNS, somatic growth, and facial structure development
Danger Signals: Cryptorchidism
Undescended Testicle
- Empty scrotal sac(s)
- most cases involve undescended testicles
- 1-2 testicles may be missing
- Testis does NOT descent w/ massage of inguinal area
- Majority cases (90%) of cryptorchidism as a/w patent processus vaginalis
- Infant should be sitting and exam room should be warm to relax muscles when massage inguinal canal
- another option is to exam child after warm bath
- ↑ risk of testicular CA of testicles are not removed from abdomen
- surgical correction (orchiopexy) necessary within 1st year of life if testicle doe snot spontaneously descend
Danger Signals: Gonococcal Ophthalmia Neonatorum
- S/sx usually show within 2-5 days after birth
- infection can rapidly spread → blindness
- DO NOT delay treatment by waiting for culture results
S/Sx
- injected (red) conjunctiva w/ profuse purulent discharge
- swollen eyelids
Majority of cases are acquired during delivery (intrapartum)
- Coinfection w/ chlamydia is common
- any neonates w/ acute conjunctivitis presenting within ≤30 days from birth should be tested for chlamydia, gonorrhea, herpes simplex, and bacterial infection
Dx:
- Gram stain
- gonococcal culture (Thayer-Martin media)
- PCR for Neisseria gonorrhoeae, herpes simplex culture, Chlamydia trachomatis of eye exudate
→ Hospitalize and tx w/ high-dose IV or IM cefotaxime
- Preferred prophylaxis is topical 0.5% erythromycin ointment (1-cm ribbon per eye) immediately after birth
- Test and treat mother and sexual partner for STDs/STIs
Danger Signals: Chlamydial Ophthalmia Neonatorum (Trachoma)
- Sx shows in 4-10 days after birth
S/Sx
- edematous eyelids
- erythematous eyes w/ profuse watery discharge initially that later becomes purulent
When obtaining sample, collect not only exudate but also conjunctival cells
- R/O concomitant chlamydial PNA
Tx:
- systemic abx (e.g., PO erythromycin base or erythromycin ethylsuccinate QID x 14 days)
- only 80% effective
- may need 2nd course
- use only systemic abx
- Prophylaxis ointment used will NOT prevent neonatal chlamydial conjunctivitis or extraocular infections ► IMPORTANT for prenatal screening and treatment
** - Reportable disease
- Test and treat mother and sexual partner for STDs
Danger Signals: Chlamydial Pneumonia
- obtain nasopharyngeal culture for chlamydia
S/Sx
- frequent cough w/ bibasilar rales
- tachypnea
- hyperinflation
- diffused infiltrates on CXR
Tx:
- Erythromycin QID x 2 weeks
- Daily follow-up
**- Reportable disease
Danger Signals: Sudden Infant Death Syndrome
- a sudden infant death in apparently healthy infants <12 months
- cannot be explained after a thorough case investigation, including a scene investigation, autopsy, and review of clinical hx
RF:
- prematurity
- low birth weight
- maternal smoking and/or drug use
- poverty
Causes: multifactorial convergence of intrinsically vulnerable infant (genetic predisposition) during a critical development period w/ exogenous stressors
To ↓ risk:
- position infants on their backs (supine)
- use a firm sleep surface
- encourage breastfeeding
- routine immunizations
- room share without bedsharing
- offer a pacifier for sleep times
- avoid soft objects and loose bedding in sleep area
- avoid smoke exposure
- avoid overheating infant
Danger Signals: Excessive Weight Loss (>10%)
- NB expected to lose weight during the first few days of life
- Weight loss can vary by feeding method and delivery type
- Infants delivered by C-section tend to lose a larger % of birth weight than vaginally delivered babies
- Formula-fed infants may lose up to 5%
- breast-fed infants may lose 7-10%
Any lose should be regained within 10-14 days
- Weight loss beyond 10% in neonates is considered abnormal
- assess infant for dehydration, electrolyte disturbances, hyperbilirubinemia, and mother/infant for lactation difficulties
** Weight loss 7-10% starts after birth but should regain birth weight in 2 weeks
Danger Signals: Dehydration
- Signs of severe dehydration:
- > 10% weight lose
- weak and rapid pulse
- tachypnea or deep breathing
- parched mucous membranes
- anterior fontanelle markedly sunken
- skin turgor showing tenting
- cool skin
- acrocyanosis
- anuria
- change in LOC (lethargy to coma)
→ Refer severely dehydrated infants to ED for IV hydration
- Severe dehydration d/t/ acute gastroenteritis is one of the leading causes of death of infants in developing world
Skin lesions: Congenital Dermal Melanocytosis
Mongolian Spots
- Most common type of pigmented skin lesions in NB
- present in almost all Asians (85-100%), >50% of Native American, Hispanic, and Black neonates
- Blue- to black-colored patches or stains
- common location: lumbosacral area, but can be anywhere on body
- may be mistaken for bruising or child abuse
- usually fade by 2-3 years
Skin lesions: Milia
Miliaria, or “Prickly Heat”
- most common in neonates
- multiple 1- to 2-mm papules located mainly on forehead, cheeks, and nose
- d/t retention of sebaceous material and keratin
- resolves spontaneously
Skin lesions: Erythema Toxcum Neonatorum
- Small pustules (whitish-yellow color), 1- to 3-mm in size
- surrounded by red base
- erupt during 2nd-3rd day of life
- located on face, chest, back, and extremities
- last from 1-2 weeks and resolves spontaneously
Skin lesions: Seborrheic Dermatitis
“Cradle Cap”
- Excessive thick scaling on scalp of younger infants
- treated by softening and removal of thick scales on scalp after soaking scalp a few hours (to overnight) w/ vegetable oil or mineral oil
- shampoo scalp and gently scrub scales w/ soft comb
- prevention is by frequent shampooing w/ mild baby shampoo and removing scales w/ soft brush/comb
- self-limited condition, resolves spontaneously within few months
Skin lesions: Faun Tail Nevus
- Tufts of hear overrlying spinal colum usually at lumbosacral area
- may be sign of neural tube defects (spina bifida, spina bifida, occulta)
- perform neuro exam on lumbosacral nerves (fecal/urinary incontinence, problems w/ gait)
- Order US of lesion to R/O occult spina bifida
Skin lesions: Cafe Au Lait Spots
- Flat light-brown to dark-brown spots >5 mm (0.5 cm)
- If ≥6 spots >5 mm (0.5 cm) in diameter are seen → R/O neurofibromatosis or von Recklinghausens’ ds (e.g., neurologic ds marked by seizures, learning disorders)
→ Refer to pediatric neurologist if spots meet the same criteria to R/O neurofibromatosis
Skin lesions: Vascular Leions - Salmon Patches
Nevus Simplex
- aka “stork bites” or “angel kisses”
- flat pink patches found on forehead, eyelids, and nape of neck
- usually appear on both sides of midline (e.g., on both eyelids or across entire nap of neck)
- blanchable but color changes w/ crying, breathing holding, and room temp changes
- Consider Beckwith-Wiedemann or FAS if glabellar lesion seen
- Typically fade by 18 months
Skin lesions: Vascular Lesions - Port Wine Stain
Nevus Flammeus
- pink-to-red
- flat
- stain like lesions located on upper and lower eyelids or on V1 and V2 branches of trigeminal nerve (CN V)
→ Referred to pediatric ophthalmologist to R/O congenital glaucoma
- blanches to pressure
- irregular in size/shape
- usually unilateral
- large lesions located on half of the facial area may be sign of trigeminal nerve involvement and Sturge-Weber syndrome (rare neurologic ds)
- lesions do NOT regress and grow w/ child
- lesions can be treated w/ pulse-dye laser (PDL) therapy
Skin lesions: Vascular Lesions - Hemangioma
Strawberry Hemangioma
- raise vascular lesions ranging in seize from 0-.5 - 4.0 cm
- bright red
- feels soft to palpation
- usually located on head of neck
- lesions often grow rapidly during first 12 months of life but majority will involute gradually over the next 1-5 years
- watchful waiting is usually strategy
- can be tx w/ PDL therapy
Vision Screening: NB Vision
- NBs are nearsighted (myopia) and have a vision of 20/400
- can focus best at a distance of 8-10 inches
- during first 2 months, infant’s eyes may appear crossed (or wander) at times (normal finding)
- if one eye is consistently turned in/out, refer to pediatric ophthalmologist
- human face is preferred by NB
- NBs do NOT shed tears because lacrimal ducts are not fully mature at birth
- Caucasian neonates are born w/ blue-gray eyes; normal for their eye color to change as they mature
- Retinas (CN II) are immature at birth and reach maturity at age 6 years
Vision Screening: Infant Screening
1. 1 month
2. 3 months
3. 6 months
4. 12 months
5. Retina and optic disc
- infant can fixate briefly on mother’s face; prefers human face
- infant will hold hands close to face to observe them; hold a bright object or a toy in front of the infant; watch behavior as the infant fixates and follows toy for a few seconds
→ avoid using object/toys that make noises when testing vision - Makes good eye contact
- turns head to scan surroundings w/ 180º visual field - makes prolonged eye contact when spoken to
- will actively turn head around 180º to observe people and surroundings for long periods
- recognizes self in a mirror and parents and fav people from a longer distance - Set fundoscope lens at 0 to -2 diopeters
- fundus appears dark orange to red (red reflex)
- red reflex of both eyes should be symmetrical in shape and color
- Set fundoscope lens at 0 to -2 diopeters
Vision - Abnormal Findings: Strabismus
- Misalignment of the eye
- Horizontal strabismus may be esotropia or exotropia
- Vertical strabismus may be hypertropia or hypotropia
- Uncorrected strabismus can result in permanent visual loss and abnormal vision such as diplopia
Tx:
- eyeglasses
- eye exercise
- prism
- eye muscle surgery
Esotropia
inward turning of the eyes
Exotropia
Outward turning of the eyes