Pediatric Urology - Exam 3 Flashcards

1
Q

What is the normal length of male genitalia? What is average? When does it begin to form? When is it completely covered by glans?

A

Normal length is 2.8cm - 4.2cm, with an average of 3.5cm

Develops beginning at 12 weeks gestation

Covers entire glans by 18-20 weeks

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2
Q

What does shallow rugae of the scrotum indicate? What does an empty scrotum indicate?

A

preterm infant

cryptorchidism

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3
Q

What is the age range for puberty in boys? What is average? What are the earliest sign of puberty?

A

9-14 years old

average 11.5

increase in testicular size and volume

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4
Q

What are later male signs of puberty?

A

pubic hair development and increase in penile length

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5
Q

What is considered male menarche?

A

Sperm in urine and nocturnal emissions occur close to end of puberty

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6
Q

What percentage of US males are circumscribed?

A

60-90% of males in the US are circumcised

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7
Q

When are circumcisions commonly performed? Why?

A

male child is between 1 and 10 days, at least 24 hours old

Infant should preferably be 24 hours old, this interval allows time for identification of other health issues that may take precedence over an elective circumcision

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8
Q

What are the 2 CI to circumcision? What is the strong caution?

A

unstable or significantly premature infants

penile abnormalities: hypospadia, chordee, concealed penis, large suprapubic fat pad

bleeding disorders is strong caution

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9
Q

What is chordee of the penis?

A

curvature of penis

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10
Q

What is hypospadias?

A

when the urethal meatus is not where it should be, usually on the posterior side of the penis

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11
Q

What are some benefits of circumcision?

A

easier genital hygiene

lower rates of UTIs during infancy

Decreased incidence of invasive penile cancer

Decreased incidence of VIRAL STDs

Decreased incidence of cervical cancer in female partners

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12
Q

Why does circumcision decrease incidence of viral STIs?

A

Variation may result from site of infection: gonorrhea/chlamydia infect urethra, while viral infections tend to involve the foreskin, where dendritic cells play a prominent role

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13
Q

What are the risks of circumcision?

A

procedure related risks

improper skin removal

bleeding/infection

glans injury

development of epidermal inclusion cysts

adhesions/scarring/skin bridge

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14
Q

What is the pain cocktail for a circumcision?

A

Local anesthesia by dorsal penile nerve block or circumferential ring block using 1% lidocaine without epinephrine or 4% lidocaine topical cream

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15
Q

______ is the blind technique for circumcision. What is sometimes the unintentional SE?

A

Mogen clamp

This type has an occasional amputation of the glans

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16
Q

What are the 2 circumcision techniques that allow for visualization of the glans? What are the major differences?

A

plastibell and gomco clamps

plastibell: plastic bell stays in place after the procedure

gomo clamps: bell shaped clamp is placed over glans during procedure while foreskin is cut but then removed at the end of the procedure

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17
Q

What is the post circumcision care? What should you NOT due?

A

Apply barrier ointment (vaseline) with diaper changes to the glans and the part of the diaper where glans would hit to reduce risk of adhesions, infection, or meatal stenosis for 2 weeks after procedure

The shaft skin should NOT be forcibly retracted

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18
Q

In an uncircumcised penis, how far does the redundant skin extend?

A

extends 1cm beyond glans

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19
Q

What is normal with regards to foreskin retraction in newborn males?

A

usually incomplete in most male infants at birth and retractability increases yearly!

90% by 3
92% by 6-7
99% by adolescence

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20
Q

What is the care of an uncircumcised penis? What should you NOT due?

A

Wash penis regularly non-irritant soap

May GENTLY retract foreskin with diaper changes and bathing to clean and dry beneath but need to replace foreskin after cleansing

Do NOT force retraction:

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21
Q

What is phimosis? Is it normal?

A

Phimosis-narrowing of the opening of the foreskin so that it CANNOT be retracted

Most phimosis is physiological at birth, most boys have physiologic phimosis: the inner surface of the foreskin is developmentally fused to the glans penis

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22
Q

______ foreskin becomes stuck behind the glans of the penis

A

paraphimosis

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23
Q

_____ inflammation of glans penis and the foreskin

A

Balanoposthitis

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24
Q

What am I? What is the tx?

A

smegma: (epithelial debris generated during desquamation) can sometimes be seen under the foreskin as pearls

tx: no intervention needed

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25
Q

What can phimosis lead to?

A

recurrent UTIs, paraphimosis, and recurrent balanoposthitis

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26
Q

What are 4 causes of phimosis?

A

Chronic nonspecific inflammatory process

Repeated infections that cause scarring and stricture

Forcible premature retraction of foreskin, causing scarring and adhesions

Balanitis xerotica obliterans (BXO

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27
Q

What is Balanitis xerotica obliterans (BXO)?What can it lead to? What is the tx?

A

a chronic dermatitis

Can lead to urethral stenosis and negatively affect sexual function

Surgery is often necessary

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28
Q

Irritation
bleeding
dysuria
painful erection
recurrent balanoposthitis
chronic urinary retention with ballooning

What am I?
What are the non sx tx?

A

phimosis

6 week BID course of topical steroid (betamethasone cream, .05%)
AND
routine stretching exercises

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29
Q

What are the sx tx options for phimosis?

A

circumcision

dorsal slit sx

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30
Q

_____ occurs when foreskin is retracted and is not replaced immediately and becomes trapped behind the corona. What should you do next?

A

paraphimosis

ED, urologic emergency!!

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31
Q

Why is paraphimosis an emergency?

A

Impairment of lymphatic and venous flow from the constricting ring of foreskin causes venous engorgement of the glans penis with swelling

Ultimately, arterial flow to the glans penis becomes compromised over a period of hours to days

aka shuts off lymph and blood flow

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32
Q

What am I?

A

phimosis

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33
Q

What am I?

A

paraphimosis

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34
Q

Edema/tenderness of glans
swelling of foreskin
constricting band of tissue proximal to glans (donut) and flaccid shaft

What am I?
What is the tx?
What is the goal?

A

paraphimosis

ED -> urology consult, with manual compression, dorsal slit or multiple punctures in glans

Goal is to replace foreskin in its normal position

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35
Q

Erythema and edema of prepuce that produces purulent discharge from preputial orifice

What am I?
What structures?
What are the normal causes?

A

BALANOPOSTHITIS (BALANITIS)

Inflammation of the glans penis and foreskin

bacterial, fungal, viral, trauma, irritation from soaps/detergents or poor hygiene

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36
Q

What is balanitis?

A

Balanitis is inflammation of glans penis only

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37
Q
A
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38
Q

Preputial swelling, tenderness, erythema
Swelling, tenderness, and erythema of glans penis, meatus, or shaft
Exudate, foul odor
Scarring between the glans and prepuce
Lymphadenopathy

What am I?
What is the tx?

A

balanoposthitis

good hygiene (sitz baths and avoid irritants)
tx based on underlying cause

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39
Q

What is the tx for GAS causing balanoposthitis?

A

amoxicillin

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40
Q

_____ is the MC penile abnormality. What is it due to? 10% of cases, there is an association with _____

A

HYPOSPADIAS

The urethral folds fail to completely or partially close and the urethral meatus opens on the VENTRAL surface of the penis, often on the DISTAL shaft

cryptorchidism

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41
Q

Can you still perform a circumcision with hypospadias? What is the tx? How old?

A

NO!!!

send to urology for surgical repair

Most urologists recommend surgical repair anywhere from 6-12 months

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42
Q

What is epispadias? How common is it? What is the tx?

A

Urethral meatus located dorsally

Much less frequent

Meatus formed on dorsum at various points along glans/shaft

surgical correction by urologist

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43
Q

____ is the most common congenital abnormality of the GU tract

A

CRYPTORCHIDISM

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44
Q

When do testicles normally descend? If one is NOT going to drop, which one is more likely?

A

Generally, spontaneously descend by 4-6 months, very rare after 6 months

Most commonly the left testicle

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45
Q

Where are the 6 places a testicle could be in the body if NOT in the scrotum?

A
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46
Q

What are the referral indications for cryptorchidism?

A
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47
Q

What should be included in the work-up in a pt with cryptorchidism?

A

initial labs

karyotype for sex determination

pelvic US

adrenal hormones: Hydroxyprogesterone, testosterone, cortisol, DHEA

LH, FSH, mullerian inhibiting substance

48
Q

What is the tx for cryptorchidism? What time frame?

A

Orchiopexy: sx to place and fix viable undescended testes into normal scrotal position

Surgery recommended asap after four months of age for congenitally undescended testis and should absolutely be completed by 1 years of age

49
Q

What is the tx for a retractile/ascending testes?

A

Retractile/Ascending testes should also be treated with orchiopexy within 6 months of finding

50
Q

Historically, _____ has not proven to be efficacious in testicular descent, often used as an adjunct. Which one in particular?

A

hormonal therapy

Can treat with hCG

51
Q

What does the success of hormonally treating cryptorchidism with hCG depend on?

A

Success is dependent on the initial location of testis, with greater success reported with lower positioned

but this tx is controversial!!

52
Q

What are complications of cryptorchidism?

A

Increased risk for developing testicular cancer (5-10 times greater risk)

Infertility

Testicular torsion

Decreased sexual function

Testicular cellular damage increases with each passing year, probably not reversible after age 4 or 5

aka the longer the testicles sit in the body, the more atrophy

53
Q

______ discrepancy between external genitalia and gonadal/chromosomal sex

A

disorder of sex development

Infants born with genitals that do not appear typically male or female or that have an appearance discordant with the chromosomal sex

54
Q

What is the MC cause of a disorder of sex development? What does it cause?

A

congenital adrenal hyperplasia

Can cause severe electrolyte and mineralocorticoid imbalances

55
Q

____ week gestation the external genitalia become differentiated. When do male external genital development complete? Female?

A

9th week

Initial male external genital development complete around 12-16 weeks

Separation of vagina and urethra is complete in female around 12 weeks

56
Q

What is the initial work-up for a pt with ambiguous genitalia?

A

Evaluation of sex chromosomes via karyotype

Assessment of gonadal function after birth:
FSH
LH
Testosterone, Dihydrotestosterone
Anti-mullerian hormone
adrenal steroids

57
Q

Why should you order an 17-OH progesterone test in ambiguous genitalia?

A

worried about adrenal steroids and concerned about salt wasting

58
Q

What are 4 ongoing medical concerns for a pt with ambiguous genitalia?

A

Potential for malignancy in gonadal tissue

Effects of altered levels of sex steroid exposure

Decreased bone mineral density

Psychosocial concerns

59
Q

What is a hydrocele? What are the 2 different types?

A

Peritoneal fluid between layers of the tunica vaginalis (serous membrane covering testes)

communicating or noncommunicating

60
Q

_____ hydrocele: A patent processus vaginalis where fluid flows into the tunica vaginalis and may increase over the course of a day or with straining/crying

A

communicating hydrocele

61
Q

_____ hydrocele: processus vaginalis closed, fluid trapped , not reducible and does not change in size/shape with crying/straining

A

noncommunicating hydrocele

62
Q

cystic scrotal mass
common in infants
with some scrotal swelling/bulge
+/- gets bigger throughout the day or with valsalva

What am I?
How do you dx?

A

hydrocele

scrotal US with transillumination

63
Q

What is the tx for hydrocele?

A

Supportive until about 1-2 years of age

then surgery if not resolved by 1-2 yrs, symptomatic or compromising skin integrity

64
Q

What are the 2 different types of hernia? Which one is MC in kids? What age range?

A

Indirect: patent inguinal canal/processus vaginalis- MC in kids

Direct: external inguinal ring only - rare in kids

Most common in boys and children < 10 months

65
Q

Intermittent bulge in groin that may have been noted at times of increased intraabdominal pressure, such as straining or crying
painless inguinal swelling

What am I?
What are the 2 major concerns?

A

inguinal hernia

incarceration and strangulation

66
Q

______ of a inguinal hernia -> firm, discrete inguinal mass can be palpated in groin. Mass usually tender and often surrounded by edema and erythema of overlying skin that CANNOT be reduced by manipulation

A

incarcerated

67
Q

______ of a inguinal hernia -> Vascular compromise of the contents of an incarcerated hernia and may see gangrene of testis/ovary or bowel loop

A

strangulation

68
Q

What is the tx for a inguinal hernia? At what level?

A

sx! to prevent incarceration as the risk increases with time

The sac is isolated from the cord structures and ligated at the level of the INTERNAL ring

69
Q

What is the presentation of a testicular torsion?

A

testicle will be lying horizontal in the scrotum and lose the cremasteric reflex

70
Q

What is the dx of choice for testicular torsion? What is the tx?

A

US with doppler!!

urgent urology consult and sx! orchiopexy to anchor testicle to scrotal wall

71
Q

What is the viability of a torsed testicule?

A

within 4-6 hours: 100% viability

after 12 hours: 20%

after 24 hours: 0% viability

72
Q

______ is most common in late adolescents but may occur in younger boys without sexual activity. What is is caused by?

A

acute epididymitis

Caused by sexual activity, heavy physical exertion, direct trauma, structural GU abnormalities

73
Q

What is a sexually active pt with acute epididymitis the likely underlying cause? What about not sexually active males?

A

Chlamydia (MC), Gonorrhea, E. Coli, viruses

mycoplasma, enteroviruses, adenoviruses

74
Q

Scrotum red
Scrotal edema
Possible inflammatory nodule felt
Normal cremasteric reflex
dysuria
urethral discharge
+/- fever

What am I?
What makes it better?

A

acute epididymitis

Pain relief with elevation of testis (positive Phren sign)

75
Q

What is included in the work-up for acute epididymitis? What dx imaging?

A

UA and urine culture

US with doppler will show increased blood flow to the epididymis

76
Q

What is the tx for suspected STD epididymitis? enteric organisms? suspected UTI?

A

STD: Ceftriaxone 250mg IM once +Doxycycline 100mg PO BID 7 days

Enteric:
Levo

UTI:
cefdinir or bactrim

77
Q

pruritis!
burning, soreness and irritation
may have discharge
erythema of vulva and vaginal mucosa with vulvar edema with/without discharge

What am I?
How do you dx?

A

vulvovaginitis

vaginal swab and microscopy

78
Q

What are risk factors for vulvovaginitis?

A

Diaper use

Broad-spectrum antibiotic use

Immunosuppression (steroid therapy, diabetes, cancer)

Adolescents with certain contraceptive devices

Poor hygiene

Bubble baths, shampoos, soaps

Choice of clothing

79
Q

What is the normal pH of a the vagina? What happens during vulvovaginitis?

A

normal pH is 4-4.5 and will be elevated in VV

80
Q

What is the tx for bacterial vaginitis? fungal?

A

metro or clinda

topical or oral fluconazole

81
Q

What is the MC pt for labial adhesions? Why do they develop?

A

Prepubertal girls in the first 5 years of life are most prone (think hypoestrogenic)

Develop as the result of fusion of the adjacent mucosal surfaces of the labia minora. Think likely d/t chronic irritation and inflammation of the hypoestrogenic vulva but the exact cause is unknown

82
Q

Often asymptomatic and typically discover at routine well child visits
Can have minute spotting due to partial dehiscense
UTI
urinary retention
altered urine stream

What I am?
How do you dx?

A

labial adhesions

through visual inspection

83
Q

What is considered uncomplicated labial adhesions? What is the tx?

A

no s/s present

then should not be treated because it is benign

84
Q

What is considered complicated labial adhesions? What is the tx?

A

If the child has accompanying symptoms such as pain on urination or ambulation, altered stream, retention, or hx of UTI

topical estrogen bid for 2 weeks and after the labia have separated then topical Vasaline to affected area daily to ensure complete healing

85
Q

What is considered an unsuccessful labial separation? What is the next step?

A

if labial separation has not occurred within 8 weeks or if cannot tolerate estrogen

Topical anesthetic, firm traction on opposing edges and manual separation can be performed. Then daily vasaline for several months

86
Q

What is the tx for thick labial adhesions?

A

will need surgical lysis by pediatric urologist or gynecologist

87
Q

______ consist of tiny areas of fusion between the foreskin and corona. What is the tx?

A

penile adhesions

Most resolve with time or gentle retraction can be used, then vasaline to prevent new adhesions from developing

88
Q

What is the tx for penile adhesions if gentle traction is NOT effective? What is the prevention?

A

low potency topical steroid

Most adhesions can be prevented by instructing the parents to retract and clean any skin covering the glans

89
Q

______ more complex fusion where foreskin adheres higher up on the glans and may result in dense adhesions. Can be visually displeasing and cause tethering of the penis. What is the tx?

A

penile skin bridge

Should be referred to pediatric urologist for lysis of adhesions via scalpel after application of topical anesthetic

aka these do NOT go away with traction

90
Q

What is the MC girl population to get an UTI? Boy? What bacteria is MC?

A

Girls >6 months have more commonly than boys

Uncircumcised boys < 3 months have more UTIs

MC: E coli

91
Q

Fever, hypothermia, poor feeding, irritability, vomiting, FTT, sepsis

What am I?

A

UTI in newborn/infant

92
Q

Abdominal/flank pain, vomiting, fever, urinary frequency, dysuria, urgency, enuresis

What am I?

A

UTI in preschool age kiddo

93
Q

frequency, dysuria, urgency
+ fever, N/V, flank pain

What am I?
When will you see CVA tenderness?

A

UTI in school-aged kiddo

rare in young children, may be seen in school-aged children

94
Q

What will the urine dipstick be positive for in a UTI? Do you always need to culture it?

A

leukocyte esterase and nitrites

YES! urine culture is required for the dx of UTI

95
Q

What age pt with an UTI can be safely managed outpt?

A

Most infants older than 2 months can be safely managed as outpatients as long as close f/u is possible

96
Q

What are the indications to hospitalize for an UTI?

A

Age less than 2 mos

Clinical urosepsis (toxic appearance, hypotension, poor capillary refill)

Immunocompromised patient

Vomiting or inability to tolerate oral medication

Lack of adequate outpatient f/u (no telephone/reliable transportation)

Treatment failure

97
Q

____ should be used if > 15% local resistance to E. coli when treating an UTI. When is cipro used? How long?

A

3rd generation cephalosporins

ceftriaxone, cefotaxime, ceftazidime, cefdinir

cipro only if pseudomonas

10 days for febrile kiddos
5 days without fever and immunocompetent

98
Q

kiddos should respond to UTI tx within ______. If they do not respond or get worse, what should you do?

A

within 24-48

broadening antimicrobial therapy may be indicated if culture/sensitivity results not yet available AND renal/bladder US to rule out renal abscess

99
Q

What are the indications for a renal and bladder US?

A

aka 3 UTIs in 12 months

100
Q

What are the indications for a Voiding Cystourethrogram (VCUG) ?

101
Q

____ is the retrograde passage of urine from the bladder into the upper urinary tract. What are these patients at an increased risk for?

A

VESICOURETERAL REFLUX

acute pyelonephritis, recurrent UTI and kidney damage due to renal scarring

102
Q

What is the prenatal finding of vesicoureteral reflux? How is the dx made postnatally?

A

suggested by the finding of hydronephrosis on prenatal ultrasound

usually made after diagnosis of a febrile UTI and reflux of urine on VCUG

103
Q

Once the dx of vesicoureteral reflux is made, what should you do next?

A

order renal function test:
UA looking for proteinuria
serum creatinine

monitor blood pressure

104
Q

What are the different grades of VUR staging?

105
Q

What is the tx for VUR grades 1-2?

A

Watchful waiting due to high rate of spontaneous resolution

May give daily abx in children not potty-trained

106
Q

What is the tx for VUR grades 3-5?

A

Antibiotic prophylaxis daily on the assumption that continuous use results in sterile urine and won’t cause renal scarring

Surgery for children with grades 4-5, and for stage 3 with no compliance with medical mgmt., or breakthrough infections on abx

Surgery corrects anatomy at the refluxing UV Junction

Generally handled by pediatric urologist

107
Q

What is enuresis defined by? What are the 2 types?

A

Defined as voiding in bed or on clothes that occurs at least twice per week for at least 3 consecutive months in a child who is at least 5 years of age

diurnal (daytime) and nocturnal (nighttime)

108
Q

What are the differences between mono symptomatic and polysymptomatic enuresis?

A

Monosymptomatic - nocturnal enuresis when no daytime symptoms

Polysymptomatic - associated with symptoms such as urgency, frequency, dribbling, or daytime enuresis

109
Q

enuresis has a strong ____ component

A

hereditary

110
Q

What are 5 reasons that may contribute to monosymptomatic nocturnal enuresis?

A

Can have decreased ADH release at night

Been reported with sleep disorders such as apnea

Anatomic abnormalities (urethral obstruction, ectopic ureters)

Strong association with constipation

Lesions of spinal cord results in neurogenic bladder

111
Q

When do you commonly see diurnal enuresis? What age group?

A

Diurnal enuresis can occur when urine is held until the last minute
and
UTIs

common in preschoolers

112
Q

What should be included as part of your enuresis work up? What are you looking for?

A

UA-> making sure urine is concentrated!!
urine culture

consider US
consider voiding cystourethrogram

113
Q

What is the mainstay of tx for enuresis tx? How long?

A

alarm therapy and CBT (the child must be motivated!!!!) Parents also need to be highly motivated!!

need to wear alarm nightly for at least 3 months!

114
Q

What is the pharm tx option for enuresis? What type?

A

Desmopressin: used mainly to treat monosymptomatic and may give more rapid short term results but relapse is common