Immunizations - Exam 2 Flashcards
When is an appropriate time to think about giving immunizations to kids?
anytime you have an encounter with kids in the office, any WWC or sick visit
How many doses of vaccines are given to a kid by age 18 months to be protected against 14 or more childhood diseases? If yes to combo vaccines, how many injections from birth to 4?
25 doses
18 injections
What 3 organizations set the standards for immunizations in the US?
Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (ACIP)
American Academy of Pediatrics (AAP)
American Academy of Family Physicians (AAFP)
What are the 2 different types of vaccines? What are the difference?
active or passive
Active immunization: induces immunity by vaccination with a vaccine or toxoid
(inactivated toxin)
passive immunization: includes transplacental transfer of maternal antibodies and administration of antibody, either as immunoglobulin or monoclonal antibody
aka mom gets the shot and passes it to baby, or IVIg
What are the 6 different types of active vaccines?
1.Live Attenuated (* Living )
2.Inactivated or Killed Viruses
3.Recombinant
4.Reassortant
5.Immunogenic Components of Bacteria
6.Toxoids
What is a live attenuated vaccine? How many doses are usually needed?
Vaccine created by reducing the virulence of a pathogen, although it is still a viable (live) vaccine
then REPLICATE in the body
immunity through a single dose
aka these type will give you symptoms of the disease
What are the 7 live attenuated vaccine examples?
Measles (MMR)
Mumps
Rubella
Varicella (chickenpox)
Intranasal Influenza (Flumist)
Rotavirus ( oral vaccine )
OPV- Oral Polio Virus
_____ and ______ can diminish response to LIVE virus vaccines if administered before the recommended interval (generally 3 months)
blood products and immunoglobulin
may inhibit the immune response
**How long should you wait between giving live vaccines?
at least 4 weeks
ex: MMR and Varicella
What is the make up of Inactivated or Killed Vaccines? Give 3 examples
Consists of virus particles which are grown in culture and then killed using a method such as heat, radiation or chemicals (formaldehyde)
Polio
Hep A
Flu shot
What is a recombinant vaccine? What are 2 examples?
Engineered viruses or bacteria into which harmless DNA encoded antigen is inserted and stimulates an immune response
Hep B
HPV
What is a reassortant vaccine? **Give 1 example. **What is super important to note about this type?
Human-Bovine reassortant:
A vaccine made by combining antigens from several strains of the same virus
Rotavirus (Rotateq): Oral vaccine
THIS IS A LIVE VACCINE
Immunogenic Components of Bacteria:
The use of ______ used to obtain immunity. What specifically?
bacterial surface components
Protein polysaccharide conjugate
What are 4 examples of Immunogenic Components of Bacteria?
Pertussis
Haemophilus Influenzae B (HIB)
Meningococcal conjugate
Pneumococcal conjugate
aka all conjugate vaccines
What is a toxoid vaccine? Give 2 examples
Bacterial toxin (usually an exotoxin) whose toxicity has been inactivated or suppressed either by chemical (formalin) or heat
Diphtheria
Tetanus
What is the preferred injection site in infants up to 3-4? _____ in children and adults 5-18 years old
anterolateral aspect of the thigh
Deltoid region
Is it safe to give multiple vaccines on the same day?
Multiple vaccines can be administered simultaneously at anatomically separate sites (different limbs or separated by >1 inch) without diminishing the immune response.
What 2 vaccines are given oral? What 2 are give subcutaneously? Which one is given ID?
oral: OPV and rotavirus
subQ: measles and yellow fever
intradermal: BCG
Does your vaccine schedule change if your kiddo was born premature?
NO!! vaccine schedule does NOT change if your kid was born premature
**How old must your kiddo be in order to receive MMR, Varicella and Hep A?
must be 1 year old
NOT 11 months and 30 days old, needs to be 12 months old
What is the birth to 4 year old vaccine schedule?
What is the vaccine schedule for age 9-17 years old?
What are the 3 types of exemptions to vaccine state laws?
medical exemption
religious
philosophical
What qualifies as a medical exemption to vaccines?
For children with valid medical contraindication to vaccine or vaccine component (ex: hx of anaphylaxis)