Pediatric Endocrinology Flashcards
T/F menarche marks the beginning of the reduction in girls’ growth rate
T
Early indicator of constitutional delay
delayed dental development
GH
Pituitary GH –> Liver IGF1 –> metabolic and bone effects –> used in screening
T/F Most SGA catch up in weight/length
T –> 10-15% of small for gestational age do not catch up by age 2
Endocrine disorders that lead to growth changes
hypothyroidism, cortisol excess, GH deficiency
Bone Age Xray
Width of epiphyses spans full width of finger and are beginning to fuse –> delayed bone age = late bloomer or disease process //normal bone age but short stature = genetically short stature
T/F Random GH evaluation is useful
F –> GH is pulsatile, mainly at night, and difficult to measure
Screening tests for growth hormone
IGF1 and IGFBP3
T/F Low IGF1 can be seen in malnutrition
T
T/F turner’s syndrome patients have close to normal intelligence
T
Elevated ESR may indicate:
Crohn’s disease
T/F can tell difference between girls/boys hormonalyl at puberty
T
T/F can tell difference between girls/boys hormonally at childhood
F –> GnRH suppression
What hormone leads to bone fusion?
estrogen
Breast enlargement in neonates
due to maternal estrogen –> usually subsides
