Peadiatrics - Neurology & Tumours Flashcards

1
Q

What are some red flags of headaches in children?

A
Pappiloedema, visual loss 
Any neurological symptoms 
Recurrent, worse in mornings
vomiting 
growth problems
< 3 years old 
diabetes insipidus symptoms
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2
Q

What are some symptoms of brain tumours in children?

A

headache and vomiting
papilloedema, squint, nystagmus
ataxia
personality/behaviour change

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3
Q

What are Wilm’s tumours and symptoms of it?

A

the most common renal tumours in childhood

Abdominal mass, haematuria
Abdo pain, anaemia, anorexia

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4
Q

What is a neuroblastoma and some common symptoms?

A

Tumour in neural crest tissue of adrenal medulla or sympathetic nervous system

pallor, weight loss, abdo mass, hepatomegaly, bone pain, limp

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5
Q

When would an enlarged lymph node in a child require biopsy?

A
No apparent cause 
persistent 
unusual spot e.g. supraclavicular 
fever, weight loss
organomegaly 
CXR - abnormal
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6
Q

What is leukemia?

What symptoms would children show?

A

When bone marrow produces increased number of abnormal or immature WBC
Children present with signs of bone marrow infiltration = fever, fatigue, frequent infections, organomegaly, anaemia, bruising

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7
Q

How common are febrile convulsions?

Initial and relapses

A

3% in 6 months - 6 years
10% risk if 1st degree relatives
30-40% have further esp. if child is younger, the convulsion occurs earlier in illness or at lower temperature, family history

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8
Q

What are complex febrile convulsions?

A

focal
prolonged > 5 minutes
multiple in 1 illness
increased risk of epilepsy to 4-12%

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9
Q

Name 3 features of a non-epileptic attack

A

resist eyes being opened, shoulder shrugging, emotional, pelvic thrusting, partially responsive, purposeful moving esp. toe tapping

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10
Q

What is a febrile convulsion?

A

epileptic seizure (usually short, generalised tonic-clonic) with fever without intracranial infection

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11
Q

How would you treat epilepsy?

A

drugs e.g. Keppra
vagal nerve stimulation
surgery

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12
Q

What is epilepsy? Name 3 types

A

excessive and hypersynchronous electrical activity and typically in cerebral cortex
gelastic, atonic, tonic, frontal lobe, focal, myoclonic, absence

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13
Q

What are some causes of cerebral palsy?

A

infection, hypoxic, haemmorhages
prenatal congenital
postnatal trauma

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14
Q

Name the 4 types of cerebral palsy

A

spastic
dyskinetic/dystonia
ataxia
mixed

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15
Q

How would you diagnose and treat absence seizures?

A

hypoventilation & EEG (3hz spike wave)

Ethosuzimide

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16
Q

How would you treat juvenile myoclonic epilepsy?

A

Keppra
Valporate - avoid in females
Lamotrigene

17
Q

What is jevnile myoclonic epilepsy? What condition is it related to?

A

10% people with absence seizures develop it
morning symptoms e.g. knocking over cereal
mycolonic seizures - brought on by sleep deprivation

18
Q

What are the 4 main types of spastic cerebral palsy?

A

UMN symptoms
hemiplegic
quadriplegic
diplegic

19
Q

What are the 4 types of MND?

A

amyotrophic lateral sclerosis (most common)
Progressive bulbar palsy (PMP)
progressive muscular atrophy (PMA)
primary lateral sclerosis (PLS)

20
Q

How would you treat MND?

A

Riluzole - sodium channel blocker
Baclofen - GABA agonist
Supportive

21
Q

What is the definition of a febrile seizure?

A

A seizure in association with a fever with no definable intracranial cause

22
Q

What is defined as a simple vs. complex febrile seizure?

A

Simple: under 15 mins, not recurring in 24 hours
Complex: over 15 minutes, focal or recurring within same febrile illness - 4-12% risk of developing epilepsy

23
Q

What are some complications of Wilm’s tumours?

A

malnutrition
metastases
hypertension
renal impairment

24
Q

What are some long term complications of childhood oncological disease?

A

haemotylogical malignancy
educational difficulties
short stature
infertility

25
Q

What would you see on an MRI for MS?

A

multiple hyperintense inflammatory white matter lesions