PCOS Flashcards
1
Q
What is PCOS?
A
2 of
- androgen excess
- infrequent periods
- cysts on ovaries on US
2
Q
What are the features of PCOS?
A
Irregular scanty periods
Androgen excess- hirsutism, acne, acanthosis nigricans
Subfertility, infertility
Obesity
3
Q
What investigations are done for PCOS?
A
Pelvic US- shows cysts on ovaries
FSH, LH, prolactin, testosterone, TSH
Insulin- elevated
4
Q
What are the general management options for PCOS?
A
Weight reduction
Combined OCP= period control, acne
5
Q
What is the management for infertility in PCOS?
A
1st= clomifene SERM 2nd= gonadotrophin
6
Q
What is clomifene?
A
Selective oestrogen receptor modulator
Give for up to 6 cycles
7
Q
What are the side effects of clomifene?
A
Ovarian hyperstimulation
Visual alterations
Vasomotor flushes
8
Q
When are gonadotrophin given?
A
IF clomifene ineffective after 6 cycles
