PCOS Flashcards
PCOS is the most common identified cause of _____ in women
infertility
patients with PCOS have an increased risk of developing what? (8)
impaired glucose tolerance
type 2 diabetes
dyslipidemia
cardiovascular disease
fatty liver disease
obstructive sleep apnea
depression/anxiety
endometrial hyperplasia and malignancy
what are 3 pathophysiology’s associated with PCOS?
altered gonadotropin behavior
increased estrogen and androgen from ovaries
insulin resistance
how to diagnose PCOS?
2/3:
irregular menstrual cycles
hyperandrogenism
polycystic appearance of ovaries on US
what should be excluded when evaluating a patient with possible PCOS? (4)
TSH
prolactin
17-OHP
free testosterone
what imaging helps diagnose PCOS?
ultrasound
what 3 labs can be done to check for at-risk conditions?
diabetes screen
lipid screen
biopsy for endometrial hyperplasia
what is the first line therapy for PCOS in obese patients?
weight loss
what is another therapy for PCOS? what are two 2nd line options?
oral contraceptives
metformin
spironolactone