pay drugs and side effects

Question 1

SSRIs can cause dyspepsia, what should you look out for?

Answer 1

peptic ulcer

Question 2

what is the name of the 5HT2 antagonist that reverses sexual dysfunction?

Answer 2

trazodone (back on traz)

Question 3

venlafaxine and duloxetine, which patients should these not be given to? what are the three side effects? (fat french drum) beach)

Answer 3

patients with cardiac problems, they cause hypertension, insomnia and cardiac arrhythmia.

Question 4

what class of AD are contraindicated in patients post MI?

Answer 4

TCAs, they have an effect on cardiac function

Question 5

what drugs increase the storage and release of 5HT and NA?

Answer 5

MAOis

Question 6

tyramine foods to avoid?

Answer 6

cheese, red wine, yoghurt, stock cubes, broad beans, pickled herring

Question 7

which drugs do MAOis have interaction with?

Answer 7

SSROs, TCAs and opiods

Question 8

mirtrazapine - when is it used?

Answer 8

1st line in patients with depression who have insomnia (tf)

Question 9

side effects of mirtazapine

Answer 9

hunger/weight gain, sedation, dry mouth/constipation, blood dycrasias (imbalances)

Question 10

which drug causes dry mouth, constipation and blood dyscarias?

Answer 10

mirtazapine

Question 11

what is a non response to an AD?

Answer 11

6 weeks

Question 12

what are the guidelines on stopping medication after the cessation of symtoms?

Answer 12

o Non response = no response after 6 weeks
o 1st episode = continue treatment for 6-12 months post resolution of all symptoms
o 2nd episode = continue treatment for 12-24 months post resolution of all symptoms
o 3rd episode = continue treatment indefinitely

Question 13

if you have 3 treated episodes of depression treated for, do you continue with treatment?

Answer 13

yes, treatment continued indefinitely

Question 14

side effects of sodium valproate? VALPROATE!

Answer 14

vomiting, alopecia, liver toxicity, pancreatitis, reduced sleep, oedema, allergic reactions/abdominal cramps, tremor/thrombocytopaenia (low platelets)

Question 15

which drug is used in bipolar depression? possibly a bad idea

Answer 15

lamotrigine

Question 16

side effects of carbamazepine?

Answer 16

drowsy. dizzy, hypothyroididm, aplastic anaemia, headaches and migraines

Question 17

which drugs is used in mania/hypomania? (brother walfrid)

Answer 17

sodium valproate

Question 18

side effects of lithium? LITHIUM + dry mouth

Answer 18

LITHIUM + dry mouth

LUEKOCYTOSIS
INCREASED THIRST (POLYDIPSIA)
TREMORS
HYPOTHYROIDISM
INCREASED URINATION (POLYURIA)
UNRELIABLE HEART (ARRYTHMIA)
MOTHERS (TERATOGENIC)

Question 19

lithium toxicity?

Answer 19

GI upset, loss of consciousness, tremor, blurred vision, seizures

Question 20

what can be given every 2-4 weeks if compliance is poor?

Answer 20

IM depot antipsychotics every 2-4 weeks

Question 21

typical anti psychotics?

Answer 21

CTFHZ

Question 22

extra pyramidal side effects?

Answer 22

acute dystonia, parkinsonism, akathisia (retlesness), tariff dyskinesia

Question 23

anti adrenergic effects? (AUN AN) (typicals)

Answer 23

• Postural hypotension
• Nasal congestion
• Inhibition of ejaculation
• Constipation
• Blurred vision
• Urinary retention and hesitation
  Sedation

Question 24

neuroleptic malignant syndrome?

Answer 24

muscle stiffness and fever

Question 25

atypicals?

Answer 25

olanzipine, risperisone, quetiapine, amisulphide, aripiprazole, clozapine

Question 26

what is metabolic syndrome?

Answer 26

triad of high blood pressure, diabetes and obesity

Question 27

clozapine - side effects

Answer 27

myocarditis, drooling, agranulocytosis

Question 28

what is often used in treatment resistant schizophrenia?

Answer 28

clozapine

Question 29

clozapine - anti cholinergic effects such as bed wetting, drooling, constipation. what is the treatment to stop these anti cholinergic effects

Answer 29

procyclidine