Pathophys--PFTS (eyeballs only)

Question 1

COPD and smoking cessation - FEV1

Answer 1

Goes down with age anyway, much faster if you smoke, but the sooner you stop smoking the slower your decrease will be

Question 2

What are predictors of PFT?

Answer 2

Sex, age, height

NOT weight

Question 3

When is post-bronchodilator response considered positive?

Answer 3

Increase in FEV1:

• 200 ml or more AND
• 15% from base FEV1

Question 4

Air trapping during exercise is also known as

Answer 4

dynamic hyperinflation

Question 5

Respiratory stridor suggests what?

Answer 5

Upper airway obstruction - vocal cord paralysis, tracheal stenosis, goiter, etc.

Question 6

How is DL is affected by the VA?

Answer 6

DL is reduced 0-25% by 50% reduction in TLC

Question 7

What does DLCO measure

Answer 7

Amount of functioning CAPILLARY BED

in contact with ventilated alveoli

Question 8

What are the requirements of single-breath DLCO?

Answer 8

inhaled VC of > 1 L and 10 seconds of breath holding

Question 9

What are some clinical applications for PFT?

Answer 9

Diff between asthma and COPD
Diff between interstitial vs chest wall
Explore PAH
Explore dyspnea with CXR infiltrate

Question 10

A negative bronchoprovocation test rules out __

Answer 10

asthma

Question 11

When is a bronchoprovocation/methacholine challenge test considered positive?

Answer 11

FEV1 dec ot 20%