Pathology/Physiology

Question 1

Common sites of coagulative necrosis

Answer 1

Kidney
Heart
Adrenals
Liver

Question 2

Caseating necrosis occurs in?

Answer 2

TB

Question 3

IL-1

Answer 3

Activates T cell, B cells

Question 4

IL-3

Answer 4

Secreted by T cell

Stimulates proliferation of haematopoietic progenitor cells

Question 5

IL-4

Answer 5

Enhances synthesis of IgE

Helper T cell proliferation

Question 6

IL-5

Answer 6

Activation of eosinophils

Enhances synthesis of IgA

Question 7

IL-6

Answer 7

Secreted by muscles + T cells + macrophages
Most important cytokine involved in coagulation activation + TNF
Mucous secretion
Pro-inflammatory

Question 8

IL-10

Answer 8

Anti-inflammatory

CSIF

Question 9

Pro-inflammatory cytokines

Answer 9

IL2
IL3
IL6
TNF

Question 10

Primary pathology for AAA

Answer 10

loss of elastic fibres from media

Question 11

Type 1 HS reaction

Answer 11

anaphylactic (IgE mediated)

Question 12

Type 2 HS reaction

Answer 12

cytotoxic (IgG mediated)

Question 13

Type 3 HS reaction

Answer 13

immune complex (IgG mediated)

Question 14

Type 4 HS reaction

Answer 14

delayed type (T cell mediated)

Question 15

DIC consumes which clotting factors

Answer 15

V + VIII + platelets

Question 16

Anti-cardiolipin antibody

Answer 16

APL

Question 17

Most common lung cancer in non smokers

Answer 17

adenocarcinoma

Question 18

HPV associated with (5)

Answer 18

cervical CA
anal CA
penile CA
vulval CA
oropharyngeal CA

Question 19

Organisms causing post splenectomy sepsis

Answer 19

Strep pneumoniae
Haemophilus influenzae
Meningococci

Question 20

CA 125

Answer 20

ovarian cancer

Question 21

CA 19-9

Answer 21

pancreatic cancer

Question 22

CA 15-3

Answer 22

breast cancer

Question 23

AFP

Answer 23

HCC, teratoma

Question 24

CEA

Answer 24

CRC

Question 25

Dercums disease

Answer 25

multiple lipomas

Question 26

Diaphragm disease caused by

Answer 26

NSAIDs

Question 27

HLA importance

Answer 27

DR > B > A

Question 28

a-1 + a-2 stimulation causes

Answer 28

vasoconstriction

Question 29

b-1 stimulation causes

Answer 29

increased cardiac contractility/HR

Question 30

b-2 stimulation causes

Answer 30

vasodilation

Question 31

d-1 stimulation causes

Answer 31

renal and splenic vasodilation

Question 32

d-2 stimulation causes

Answer 32

inhibition of noradrenaline release

Question 33

Intrinsic pathway blood test

Answer 33

APTT

Question 34

extrinsic pathway blood test

Answer 34

PT

Question 35

Intrinsic pathway factors

Answer 35

8,9,11,12

Question 36

Extrinsic pathway factors

Answer 36

7

Question 37

Common pathway factors

Answer 37

2,5,10

Question 38

DIC affects which clotting factors

Answer 38

1,2,5,8,11

Question 39

Cells responsible for release of gastric acid

Answer 39

parietal cells

Question 40

Dietary iron absorbed where

Answer 40

duodenum

Question 41

normal intragastric pH

Answer 41

2

Question 42

JVP a wave

Answer 42

atrial contraction

Question 43

JVP c wave

Answer 43

closure of tricuspid valve

Question 44

JVP v wave

Answer 44

passive filling of atrium

Question 45

JVP x descent

Answer 45

ventricular systole

Question 46

JVP y descent

Answer 46

opening of tricuspid valve