Pathology of Rashes Flashcards
1
Q
What causes acne?
A
- Increased Androgens at puberty
- Increased Androgen sensitivity of sebaceous glands
- Keratin plugging of pilosebaceous units
- Infection with anaerobic bacterium corynebacterium acnes
2
Q
What is Rosacea?
A
Commoner in females Recurrent facial flushing Visible blood vessels Pustules Thickening of skin - rhinophyma
3
Q
What is the primary feature of IMMUNOBULLOUS DISEASES? Give 3 examples.
A
blisters
e.g. PEMHIGUS
BULLOUS PEMPHIGOID
DERMATITIS HERPETIFORMIS
4
Q
What is the end result of Pemphigus vulgaris?
A
ACANTHOLYSIS
5
Q
Is there acantholysis in Bullous pemphigoid
A
No
6
Q
What has a Strong association with coeliac disease ?
A
dermatitis herpetiformis
7
Q
Which is deeper, phemphigoid or phemphigus?
A
phemphigoiDDDDD (Deep)
8
Q
Treatment of pemphigoid/pemphigus?
A
Systemic steroids
Other immunosuppressive agents: azathioprine, ciclosporin, mycophenolate
In pemphigoid: tetracycline antibiotics, nicotinamide
Topicals: emollients, topical steroids