Allergy and Skin

Question 1

What word means “Immune response that causes collateral damage to self?”

Answer 1

hypersensitivy

Question 2

Which type is IgE mediated?

Answer 2

Type 1

Question 3

Which type is IgG mediated cytotoxic hypersensitivity?

Answer 3

Type 2

Question 4

Which type is immune complex mediated?

Answer 4

Type 3

Question 5

Which type is Cell mediated?

Answer 5

Type 4

Question 6

Does type 1 reaction have a consistant reaction with each exposure?

Answer 6

Yes

Question 7

Is type 1 an immediate or delayed reaction?

Answer 7

immediate

Question 8

“hives”, “wheals”, “nettle rash” are all words for what?

Answer 8

urticaria

Question 9

How quickly do lesions appear in urticaria?

Answer 9

within 1 hour

Question 10

Which term describes localised swelling of subcutaneous tissue or mucous membranes (non itchy)?

Answer 10

angioedema

Question 11

Give 4 investigations that should be done regarding anaphylaxis.

Answer 11

Specific IgE (RAST) – specificity & sensitivity 70-75%
Skin prick or prick-prick testing
Challenge test
Serum mast cell tryptase level (during anaphylaxis)

Question 12

How much adrenaline should be given for anaphylaxis?

Answer 12

300µg adults

150µg children

Question 13

What type is Allergic contact dermatitis?

Answer 13

Type 4

Question 14

Is type 4 immediate or delayed?

Answer 14

delayed

Question 15

When does onset of reaction typically occur in type 4?

Answer 15

24hours

Question 16

Which chemical is responsible for henna and hair dyeing?

Answer 16

PPD - type 4 reaction