Pathology of Pulmonary infection Flashcards

1
Q

List the 3 types of micro organisms that can cause infection.

A

Primary- (bad news)
Facultative
-Opportunistic

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2
Q

Name some URT infections

A
Coryza- common cold
Sore throat syndrome
Acute Laryngotracheobronchitis ( croup)
Laryngitis
Sinusitis
Acute Epiglottitis
(all of the above pathology stems from inflammation)
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3
Q

What is the most severe type of URT infection?

A

Acute Epiglottitis

  • Group A beta- haemolytic Streptococci
  • Haemohilus influenzae (type b)
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4
Q

Name the lower Respiratory Tract infections.

A
  • Bronchitis
  • Bronchiolitis
  • Pneumonia
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5
Q

Name the componenets of the macrophage-mucociliary escalator system

A
  • Alveolar Macrophages
  • Mucociliary Escalator
  • Cough Reflex
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6
Q

What happens to the mucociliary escalator during a viral infection?

A

Stripped clean, Why bacterial infections often follow consequently.

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7
Q

What are the three classifications of pneumonia?

A

Anatomical
Aetiological
Microbiological

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8
Q

What are the classifications of aetiological pneuomia?

six

A
  • Community acquired pneumonia
  • Hospital aquired (NOSOCOMIAL) pneumonia
  • Pneumonai in immumocompromised
  • Atypical pneumonia
  • Aspiration pneumonia (Vom)
  • Recurrent Pneumonia - somethings very wrong.
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9
Q

Describe the patterns of pneumonia

A

Bronchopneumonia
Segmental
Lobar

Hypostatic -lots of fluid in lung
Aspiration
Obstructive, retention, endogenous lipid

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10
Q

Describe Bronchopneumonia

A

Patchy infection of small airway from bacterial infection. Happens when laminar airflow changes to diffusion.

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11
Q

What are some causes of bronchpneumonia?

A

From circ failure

From Bronchitus

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12
Q

Describe lobar Pneumonia

A

Much more agressive, more invasive fills a whole lobe if possible until it reaches pleura.

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13
Q

What are the complications of pneumonia?

A

Organisation
Lung abscess
Bronchiectasis

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14
Q

What can happen due to organisation?

A

Mass lesion
COP (cryptogenic organisating pneumonia )
Constrictive bronchiolitis

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15
Q

Name some organisms which can cause a lung abscess?

A

Staph aureus, some pneumococci, Klebsiella

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16
Q

Bronchiectasis is what?

A

Pathological dilation of bronchi

17
Q

What can cause Bronchiectasis?

A
  • Severe Infective episode
  • Recurrent infections
  • Proximal bronchial obstruction
  • Lung Parenchymal destruction
18
Q

What are the feaures of bronchiectasis

A
  • Cough
  • Abundant purulent foul sputum
  • haemoptysis
  • Coarse crackles
  • Clubbing
19
Q

How to treat bronchiectasis

A

Postural drainage
Antibiotics
Surgery

20
Q

Name the causes of aspiration pneumonia

A
  • Vommiting
  • Oesophageal lesion
  • Obstetric Anaesthesia
  • Neuromuscular disorders
  • sedation
21
Q

What is the most common place for aspiration pneumonia?

A

Apical centre of right lower lobe

22
Q

Name some opportunistic infections

A
  • Low grade bacterial pathogens
  • CMV
  • Pneumocystis jirovecii
  • Other fungi and yeasts