Pathology 4 Flashcards
Most common Skin cancer
Basal cell carcinoma
Locally invasive, ut almost never metastasizes. Pink Pearly nodules, commonly with telangiectasias
Basal Cell Carcinoma
Palisading nuclei
Basal Cell Carcinoma
Lower Lip
Squamous cell carcinoma
Cup-shaped tumor filled with keratin debris
Keratoacanthoma
Precursor to squamous cell carcinoma
Actinic keratosis
keratin pearls, skin cancer
Squamous cell carcinoma
ABCs of melanoma
Asymmetry, Border irregularity, Color variation, Diameter >6mm
BRAF V600E mutation
Melanoma (unresectable, metastatic type)
Melanoma Tx
Vemurafenib, a BRAF kinase inhibitor
Radial Growth
horizontal growth along epidermis and superficial dermis, low risk of metastasis
Vertical Growth
growth downward into dermis, increases risk in metastasis
Melanoma on the palms and soles in dark skinned people, not related to UV light
Acrolentiginous melanoma
A benign soft tissue tumor of adipose tissue
Lipoma
Malignant tumor or adipose tissue
Liposarcoma