Anatomy & Physiology Flashcards
Epidermis Layers from Surface to Base
Stratum Corneum, Lucidum (anucleate cells), Granulosum, spinosum (spines are desmosomes), basale (stem cells) Californians Like Girls in String Bikinis
Location of hair shaft, sweat glands, sebaceous glands
Dermis
Tight Junctions
Zonula Occludens, prevents paracellular movement of solutes; composed of claudins and occludins
Adherens Junctions
Zona Adherens, below tight junction, forms “belt” connecting actin cytoskeletons of adjacent cells with Cadherins
Calcium-dependent adhesion proteins
Cadherins
macula adherens, structural support via keratin interactions
Desmosome
Autoantibodies to desmosome
Pemphigus Vulgaris
Membrane proteins that maintain integrity of basolateral membrane by binding to collagen and laminin in basement membrane
Integrins
Connects keratin in basal cells to underlying basment membrane
Hemidesmosome
Autoantibodies to Hemidesmosome
Bullous Pemphigoid
Anterior Drawer Test
ACL injury
Posterior Drawer Test
PCL injury
Abnormal Passive Abduction (Valgus Stress)
MCL Injury
Abnormal Passive Adduction (Varus Stress)
LCL injury
McMurray test
Pain on external rotation of tibia - medial meniscus
Pain on internal rotation of tibia - lateral meniscus
Unhappy Triad
ACL, MCL and medial meniscus
Most common contact sports injury due to lateral force applied on planted leg
ACL attachment on Tibia
Anterior
PCL attachment of Tibia
Posterior
Ischial Spine
Pudendal Nerve Block to relieve pain during delivery
McBurney Point
2/3 distance between umbilicus and ASIS just prox to ASIS
Iliac Crest
Lumbar Puncture
Suprascapular nerve
Supraspinatus and infraspinatus
Shoulder Muscles of Rotator Cuff
Supraspinatus, infraspinatus, teres minor, subscapularis
Medially rotates and adducts arm
subscapularis (subscapular nerve)
Laterally rotates and adducts arm
Teres Minor (axillary nerve)
Laterally rotates arm, pitching injury
Infraspinatus
Initially Abducts arm; most common rotator cuff injury
Supraspinatus
Wrist bones Starting thumb side
Scaphoid, Lunate, Triquetrium, pisiform
Trapezium Trapezoid, capitate, hamate
Palpated in Anatomical Snuff Box
Scaphoid
Most commonly fractured carpal bone and is prone to avascular necrosis owing to retrograde blood supply
Scaphoid
Lunate Dislocation
Acute Carpal tunnel syndrome
Wrist bone damage when falls on outstretched hand
Hook of hamate, can cause ulnar nerve injury
Carpal Tunnel Syndrome
entrapment of median nerve
Guyon Canal Syndorme
Compression of the ulnar nerve at wrist or hand
Tear in C5-6, upper trunk - lateral traction on neck during during delivery
Erb Palsy
Muscles affected in Erb Palsy
Deltoid, supraspinatus, infraspinatus, biceps brachii
Traction or tear in lower trunk, C8-T1
Klumpke Palsy
Pulling infant out with their arm
Adults trying to catch themself from falling from a tree
Klumpke Palsy
Total Claw Hand
Klumpke Palsy
Muscle affected in Klumpke Palsy
lumbricals, interossei, thenar and hypothenar
Winged Scapula
Lesion of Long thoracic nerve, axillary node dissection after mastectomy, stab wounds
Muscle affected in Winged scapula
Serratus Anterior