Pathogen & Disease Test: Antimicrobial Drugs Flashcards

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1
Q

Antimicrobial Agent

A

an agent that kills microorganisms or stops their growth

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2
Q

Microbicides

A

agents that kill microbes

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3
Q

Bacteriostatic Agents

A

agents that prevent microbes from growing

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4
Q

Disinfectants

A

non-selective antimicrobial agents that kill a wide range of microbes on non-living surfaces to prevent the spread of illness

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5
Q

Antiseptics

A

antimicrobial agents that are applied to living tissue and help reduce infection during surgery

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6
Q

Antibiotics

A

antimicrobial agents that destroy microornganisms within the body

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7
Q

Antimicrobial Drugs

A

include synthetic (manufactured) drugs as well as drugs produced by bacteria and fungi, called antibiotics

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8
Q

Bactericidal Agents

A

agents that kill microbes directly

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9
Q

Selective Toxicity

A

killing the pathogen without damaging the host

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10
Q

Narrow-Spectrum Antimicrobial Drugs

A

affect only a limited number of microbial types

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11
Q

Broad-Spectrum Antimicrobial Drugs

A

affect a large number of microbial species

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12
Q

What are the 4 ways Antimicrobial Agents work to kill microbes?
How do Antimicrobial Drugs work?

A
  1. Damage cell walls
  2. Inhibit protein synthesis
  3. Damage plasma membrane
  4. Inhibition of enzyme activity
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13
Q

What are the 4 ways Antimicrobial Agents work to kill microbes: Damage Cell Walls

A

the synthesis of new cell walls during cell division is inhibited
EX. penicilin, vancomycin, cephalosporins, bacitracin

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14
Q

What are the 4 ways Antimicrobial Agents work to kill microbes: Inhibit Protein Synthesis

A

the process of translation is interfered with

EX. erythromycin, tetracyclines, chloraphenicol, streptomycin

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15
Q

What are the 4 ways Antimicrobial Agents work to kill microbes: Damage Plasma Membrane

A

the plasma membrane may be ruptured

EX. nystain, miconazole, polymyxin B

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16
Q

What are the 4 ways Antimicrobial Agents work to kill microbes: Inhibition of Enzyme Activity

A

the synthesis of essential metabolites is inhibited

EX. sulfanillamide, trimethoprim

17
Q

Zone of Inhibition

A

where there is little or no bacterial growth on a nutrient agar medium

18
Q

What are the requirements of an “ideal” anti-microbial drugs?

A

the ideal drug has selective toxicity, killing the pathogen without damaging the host

19
Q

Antibiotic Resistance

A

when germs like bacteria and fungi develop the ability to defeat and overcome the drugs designed to kill them

20
Q

Why do antibiotics not work against viruses?

A

because viruses have different structures and replicate in a different way that bacteria; they have a protective coating/ don’t have cell walls that can be attacked by antibiotics