Patho Exam 3 Flashcards
1
Q
- Function of the Kidney
- What is the general renal rule?
- What is the function of the glomerulus
A
- filter plasma, reabsorb/secrete, forms filtrate of protein free fluid, regulate filtrate to maintaine body fluid volume, excrete waste
- Decrease protein.
- Filtration
2
Q
- How is it driven?
- What does the proximal tubule do?
- What does the proximal tubule secrete?
A
- hydrostatic pressure
- reabsorption of sodium/glucose, reabsorps 180L/day
- H+ and foreign substances
3
Q
- What is the loop of henle?
- Descending loop
- Ascending loop
A
- concentration
- water reabsorption, Na+ diffuses in
- Na reabsorps, (active transport), water stays in
4
Q
- Distal tubule
- Collecting tubule requires what?
- What does it do
A
- Selective reabsorption, potassium and hydrogen ions
- ADH
- H2O
5
Q
- Normal pH in urinalysis
- What do most bacteria favor?
- Protein in the urine represents?
A
- 5-8
- alkaline
- kidney disease, increasus BUN
6
Q
- Specific gravity
- What end is more concentrated
- Glucose in the urine represents
A
- 1.010-1.025
- higher the number
- diabetes, stress
7
Q
- What are ketones
- What does it represent if in urine
- Nitires in the urine represent
A
- fats
- acute metabolic demand, stress, DKA (atkin’s diets)
- bacterial infection (convert nitrates-nitrties)
8
Q
- WBC in the urine
- Should RBC’s be present in urine?
- Creatnine clearance (24hr urine collection)..
A
- UTI
- no
- glomerular filtration rate, renal disease
9
Q
- How do you measure kidney function?
- Normal creatnine level
- What is BUN
A
- Creatnine and BUN
- 0.6 - 1.2
- end product of protein metabolism, index
10
Q
- Normal BUN
- Types of Upper UT obstruction
A
- 7 - 18 mg/dL
- Stricture, stone, tumor fibrosis, hydroureter, hydronephrosis, urinary stasis above the level of obstruction
11
Q
- What is hydroureter
- what is hydronephrosis
- What can happen if urinary stasis?
A
- (thick/fat), allows back flow. Dilation of ureter.
- Dilation of renal pelvis
- infection, staph, stones, dilation of ducts, atrophy of kidney
12
Q
- Within 7 days of obstruction
- Within 28 days of obstruction
- If kidney does not retain bicarb or excrete hydrogen, what acid-base imbalance?
A
- enlargement and fibrosis
- glomeruli damaged
- metabolic acidosis
13
Q
- If the kidney does not conserve Na but retains potassium?
- What does kidney stone obstruction have to do with?
- 3 types of kidney stones
A
- hyponatremia, hyperkalemia
- Diet, genetics, food intake
- Calcium, Struvite (mg,large), Uric Acid (gout)
14
Q
- Manifestation of kidney stones
- Diagnostics
- Prevention
A
- pain, renal colic, N/V, hematuria (gross or microscopic), flank uoq
- xray, ultrasound, IV pilogram (dye will outline stone)
- fluid intake, caclium (decrease oxelate (cut back on spinach chard, choco)
15
Q
- TX Renal
- Lower Ut obstruction types
- What is a neuorogenic comprised of
A
- lithotripsey (shock waves) not invasive, Stent- cath opens tube to pass urine, stone removal
- neurogenic, anatomic
- dysnergia, hypotonic bladder, detrusor hyperreflexia (empties automatically, overflow)
16
Q
- What is anatomic obstruction
- Manifestation of lower obstruction
- What is an adenoma
A
- rectocele (prolapse of rectum), cystocele (bladder drops ontio itself and causes blockage)
- nocturia, polyuria, urgency/hestiation, incomplete
- common tumor, benign tendency to become malignant
17
Q
- Renal Cell carcinoma
- Renal Tranistional cell carcinoma?
- Demographics
A
- most common renal cancer
- rare
- males, diabetes, obesity, uncontrolled htn
18
Q
- S/Sx of renal tumor
- Bladder tumors common or not?
- Where are bladder tumors located?
A
- Frank blood, bloody urine (slight or microscopic)
- most common
- epithelium of the bladder
19
Q
- Risk factors for bladder tumor
- What ia a UTI
- What is acute cystitis
A
- Male >60, smoking, Aniine dyes (leather couch), secondary of cervix/prostate
- inflamed epithelium caused by bacteria
- Inflammation of the bladder
20
Q
- Common bacteria in acute cystitis?
- Manifestation of acute cystitis
A
- E. Coli
- sphincter inflamed, urgency, hematuria, cloudy urine, flank pain, confusion
21
Q
- Tx of Acute Cystitis
- What is pyelonephritis
A
- C/S test, analgesic (pyridium), fluid intake, avoid sugary drinks, Cranberry juice (antimicrobe)
- infection of 1 or both upper urinary tracts
22
Q
- Where does puelonephritis occur
- Is it unilateral or bilateral
A
- Upper Tract
- could be both