[PATHO] DISEASES OF EYE Flashcards
Premature infant
oxygen therapy
neovascularization & retinal detachment
impaired vision
Retrolental fibroplasia
night blindness
hyperpigmentation of eye without inflammation
retinitis pigmentosa
retinitis pigmentosa is caused by
mutation in gene encoding rhodopsin
loss of rods causes night blindness
inheritance patterns of retinitis pigmentosa
autosomal dominant
autosomal recessive
sex-linked recessive
histologically what can be found in an eye affected by retinitis pigmentosa
1-disappearance of rods & cons
2-2ry proliferation of pigment epithelium
3-ingrowth of glial membrane on optic disc
acute suppurative inflammation of sebaceous glands of Zeis, apocrine glands of Moll & eyelash follicles
stye/ externalhordeolum
acute suppurative inflammation of meibomian glands
internal hordeolum
chronic inflammation of meiobomian glands
chalazion
chalazion occurs due to
obstruction of drainage of secretions
chalazion inflammatory process begins with
destruction of meibomian glands & duct
tarsal plate affection
histologically what can be seen in case of chalazion
granuloma located in tarsal plate w/ fat globules (lipogranuloma appearance)
acute suppurative intraocular inflammation exogenous or endogenous in origin
endophthalmitis
acute stage of conjunctivitis is cc by
corneal edema
inflammatory cells infiltration
decreased corneal transparency
chronic stage of conjunctivitis is cc by
small BVs proliferation in cornea
plasma cells + lymphocytes infiltration
pannus formation
in trachoma C.trachomatis targets
conjunctival epithelium
trachoma can be recognized by
intracytoplasmic inclusions
lymphoid follicles
trachoma is cc by (8)
1-intracytoplasmic inclusions
2-lymphoid follicles
3-chronic inflam cells infiltrate
4-macrophages
5-corneal+conjunctival scarring
6-eyelid deformity
7-inturned eyelashes
8-blindness
inclusion conjunctivitis causes
mild keratoconjunctivitis
inclusion conjunctivitis is caused by
C. oculogenitalis
chronic granulomatous lesion of eye
granulomatous uveitis
bilateral diffuse granulomatous uveitis following penetrating injury to one eye
sympathetic ophthalmia/uveitis
sympathetic ophthalmia/uveitis pathogenesis
1-trauma to one eye
2-auto sensitivity reaction to injured uveal tissue
3-visual loss in both eyes
histologically what can be seen in case of sympathetic ophthalmia
epithelioid cells
lymphocytes
no necrosis
no neutrophils
no plasma cell infiltration
in case of sympathetic uveitis, if lens is injured it develops into
phacoanaphylactic endophthalmitis