Path7 Flashcards
Tumor Markers
PSA
Prostate-Specific Antigen
Used to follow up prostate carcinoma
*can also be elevated in BPH and Prostatitis
Prostatic Acid Phosphatase
Prostate Carcinoma
CEA
CarcinoEmbryonic Antigen
Very Non-Specific but
Produced by ~ 70% of Colorectal and Pancreatic Cancers
Also produced by gastric, breast, and medullary thyroid carcinomas
alpha-fetoprotein
Hepatocellular carcinomas
Nonseminomatous germ cell tumors (e.g., testis, ovary)
beta-hCG
Hydatidiform moles
Choroicarcinomas
(Gestational trophoblastic disease)
CA-125
Ovarian cancer
S-100
Melanoma
Neural Tumors
Schwannomas
Alkaline phosphatase
Metastases to:
- bone
- liver
Paget’s disease of bone
Bombesin
Neuroblastoma
Lung
Gastric
TRAP (Tartrate-Resistant Acid Phosphatase)
Hairy cell leukemia – B-cell neoplasm
CA-19-9
Pancreatic adenocarcinoma
Calcitonin
Medullary thyroid cancinoma