Path7 Flashcards

Tumor Markers

1
Q

PSA

A

Prostate-Specific Antigen
Used to follow up prostate carcinoma

*can also be elevated in BPH and Prostatitis

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2
Q

Prostatic Acid Phosphatase

A

Prostate Carcinoma

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3
Q

CEA

A

CarcinoEmbryonic Antigen
Very Non-Specific but
Produced by ~ 70% of Colorectal and Pancreatic Cancers
Also produced by gastric, breast, and medullary thyroid carcinomas

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4
Q

alpha-fetoprotein

A

Hepatocellular carcinomas

Nonseminomatous germ cell tumors (e.g., testis, ovary)

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5
Q

beta-hCG

A

Hydatidiform moles
Choroicarcinomas
(Gestational trophoblastic disease)

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6
Q

CA-125

A

Ovarian cancer

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7
Q

S-100

A

Melanoma
Neural Tumors
Schwannomas

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8
Q

Alkaline phosphatase

A

Metastases to:
- bone
- liver
Paget’s disease of bone

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9
Q

Bombesin

A

Neuroblastoma
Lung
Gastric

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10
Q

TRAP (Tartrate-Resistant Acid Phosphatase)

A

Hairy cell leukemia – B-cell neoplasm

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11
Q

CA-19-9

A

Pancreatic adenocarcinoma

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12
Q

Calcitonin

A

Medullary thyroid cancinoma

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