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Block 5 Material > Path - Cells And Tests > Flashcards

Path - Cells And Tests Flashcards

1
Q

red test tube cap

A

Glass=nothing
Plastic=clot activator

Serology
Blood bank
Chemistry tests

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2
Q

Red/gray test tube cap

A

No anticoagulant but does have clot activator gel for separating cells from serum

Serology
Chemistry tests

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3
Q

Light blue test tube cap

A

Citrate anticoagulant

Coagulation tests

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4
Q

Purple test tube cap

A

EDTA anticoagulant

CBC
Ammonia

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5
Q

Green test tube cap

A

Heparin anticoagulant

Blood gases
Chemistry tests

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6
Q

Gray test tube cap

A

Fluoride with oxalate anticoagulant

Glucose
Lactate

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7
Q

Yellow test tube cap

A

Acid citrate dextrose (ACD)
Blood bank studies

or
Sodium polyanethol sulfate (SPS)
Blood cultures

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8
Q

Dark blue test tube cap

A

Nothing
Stopper is usually specially treated

Trace elements
Nutritional studies
Toxicology

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9
Q

Sensitivity equation

A

100 X (TP/(TP+FN))

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10
Q

Specificity equation

A

100 X (TN/(TN+FP))

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11
Q

PPV equation

A

100 X (TP/(TP+FP))

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12
Q

NPV equation

A

100 X (TN/(TN+FN))

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13
Q

Number of existing cases of a disease in a population

A

Prevalence

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14
Q

Number of new cases of a disease in a population per unit time

A

Incidence

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15
Q

As prevalence increases, PPV ___

A

Increases

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16
Q

Screening tests require high ___

Confirmatory tests require high ___

A

Sensitivity

Specificity

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17
Q

More sensitive = more chance of ___

More specific = more chance of ___

A

FP

FN

18
Q

True anemia is marked by what characteristic of RBCs?

A

Decreased RBC mass

19
Q

Relative anemia is due to __

Causes?

A

Increased plasma volume

Pregnancy
Excessive hydration
Macroglobulinemia

20
Q

Severe symptoms of anemia

A

Chest pain
Angina
Heart attack
Fainting

21
Q

Trauma causes what kind of anemia?

A

Acute

22
Q

What is the most common cause of anemia of insufficient production? Others?

A

Iron deficiency

B12 or Folate deficiency
bone marrow suppression or replacement
-parvovirus B19
-cancer

23
Q

Hereditary membrane abnormality:

A

Elliptocytosis

24
Q

Hereditary hemoglobin abnormality:

A

Thalassemia

25
Q

Extravascular vs intravascular causes of RBC destruction

A

Extra-warm autoimmune hemolytic anemia

Intra-RBC fragmentation disorders

26
Q

Large number of blue cells, which are immature RBCS, due to an increase in demand

A

Hyperproliferative

27
Q

Definitions:
Variation in size of RBCs?
Shape?

A

Anisocytosis

Poikilocytosis

28
Q

Anemia of chronic disease:

Morphologic characteristics

A

None

29
Q

Thalassemia

A

quantitative defects of hemoglobin
Reduced globin chain synthesis
Alpha and beta

30
Q

Beta thalassemia major

Characteristics

A 
Severe microcytic hypochromic anemia
Anisocytosis
Poikilocytosis
Many uncleared RBCs
Polychromasia
31
Q

Cytoskeletal abnormalities cause

A

Hereditary spherocytosis

32
Q

Small nuclear remnants
Typically single
Normal in neonates

A

Howell Jolly bodies

33
Q

Iron-containing mitochondrial remnants

Small clusters near cell periphery

A

Pappenheimer granules

34
Q

MCV below normal
Above normal
Normal

A

Microcytic
Macrocytic
Normocytic

Mean cell volume

35
Q

Most common cause of microcytic hypochromic cells

A

Iron deficiency

36
Q

Cells in hemoglobin C disease

A

Target cells
Hemoglobin C crystals
Irregularly contracted cells
Spherocytes

37
Q

Degmacyte vs schistocyte

A

Bite cell

Fragmented cell

38
Q

Aggregates of denatured hemoglobin

A

Heinz bodies

39
Q

Dacrocytes

A

Tear drop cells

40
Q

Blue gray color of immature RBCs due to residual ribosomal material

A

Polychromasia

41
Q

Aggregates of ribosomes
RNA
All over the cell

A

Basophilic stippling

Block 5 Material (17 decks)

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