Path 1 Quiz 5 Fat-soluble Vitamins Flashcards
Where in the body is Vitamin A found?
Liver
What are the 3 forms of Vitamin A
Retinol
Retinal
Retinoid Acid
Function of Retinol
Storage and transport form
90% is stored in the liver
Stored for 6 months
Function of Retinal
Maintains normal vision in dim light
- important in the production of visual pigments in photoreceptors
Retinonic Acid
Important in determining lifespan of epithelial cells
potentiation and differentiation of specialized epithelial cells, mainly mucous secreting cells
Where is retinol found?
Orange and red plants such as carrots
What does retinol in food must be eaten with to be absorbed?
It must be eaten with Fat for absorption
Carotinoids
Natural precursor for retinal - example betacarotene = Provitamin A
Retinoids
form of Provitamin A
Syntehtic/artificial, avoid these - can lead to teratogenic affects
Rhodopsin
Rods
Iodopsin
Cones
Deficiency in retinal leads to
Night Blindness
Deficiency in Retinoid acid leads to
Xerophthalmia Xeroxes Squamous Metaplasia - Follicular and popular dermatosis - Pulmonary Infection - Nidus formation
Xerophthalmia
Dry eye - obstruction of lacrimal gland
Xeroxes
Dryness pathology
Sloughed epithelial cells of conjunctiva form plaques close to cornea leading to BITOT’S SPOTS ===> KERATOMALACIA —-> ulceration of cornea —-> blindness via CT
Define Keratomalacia
Softening damage to the cornea
Bitot’s spots is closely related to
Vitamin A deficiency of retinoid acid and is apart of xeroxes - located in the eyeball
AKA for nightblindness
Chicken blindness
Vitamin A helps with the normal life span of epithelial cells T/F
True
The most common development of retinoic acid deficiency is
Xerophthalmia
Enhancement of immunity to infections, particularly in children are reduced by Vitamin A by _____ % It fights the morality of 3 diseases they are
Measles
Pneumonia
Infectious diarrhea
What are the two types of Hypervitaminosis A
Acute
Chronic
Characteristics of acute hypervitaminosis
Characterized by increased intracranial pressure/triad
Headache associated with nausea and vomiting and papilledema
Characteristics of chronic hypervitaminosis
weight loss Nausea, vomiting Dryness of mucosa of lips bone and joint pain Hepatomegaly Liver Fibrosis Hyperostosis aka dish aka forester's disease