Path 1 Quiz 5 Fat-soluble Vitamins Flashcards
Where in the body is Vitamin A found?
Liver
What are the 3 forms of Vitamin A
Retinol
Retinal
Retinoid Acid
Function of Retinol
Storage and transport form
90% is stored in the liver
Stored for 6 months
Function of Retinal
Maintains normal vision in dim light
- important in the production of visual pigments in photoreceptors
Retinonic Acid
Important in determining lifespan of epithelial cells
potentiation and differentiation of specialized epithelial cells, mainly mucous secreting cells
Where is retinol found?
Orange and red plants such as carrots
What does retinol in food must be eaten with to be absorbed?
It must be eaten with Fat for absorption
Carotinoids
Natural precursor for retinal - example betacarotene = Provitamin A
Retinoids
form of Provitamin A
Syntehtic/artificial, avoid these - can lead to teratogenic affects
Rhodopsin
Rods
Iodopsin
Cones
Deficiency in retinal leads to
Night Blindness
Deficiency in Retinoid acid leads to
Xerophthalmia Xeroxes Squamous Metaplasia - Follicular and popular dermatosis - Pulmonary Infection - Nidus formation
Xerophthalmia
Dry eye - obstruction of lacrimal gland
Xeroxes
Dryness pathology
Sloughed epithelial cells of conjunctiva form plaques close to cornea leading to BITOT’S SPOTS ===> KERATOMALACIA —-> ulceration of cornea —-> blindness via CT