Path 1 Quiz 5 C Vitamin Flashcards
Vitamin C is known as
Ascorbic Acid
Vitamin C can not be produced in the body T/F
True
What are the functions of Vitamin C
Hydroxylation of pro collagen
Synthesis of Collagen peptides
Free-radical scavenger - powerful antioxidant
What is proline?
it is a Amino Acid that is a major constitute of most proteins esp collagen
Pro collagen is full of proline - proline is hydroxylated by vitamin C to become
Hydroxyproline
What is hydroxyproline’s function?
Makes CT strong - increases the tensile strength
If proline is not hydroxylated this results in
weak proline = collagen is weak - esp. in blood vessels which can lead to bleeding
Vitamin C is a powerful antioxidant is works with what other vitamin and trace mineral
Vitamin E
selenium
*prevents the destruction of cell membrane
* reduces oxidation of LDLS decreasing atherosclerosis
A deficiency of Vitamin C will lead to what disease?
Scurvy
List the 3 components of Scurvy that a pt. would present with via Vitamin C deficiency
1) Bleeding Diathesis:
- Petchiae and ecchymosis
- bleeding gums
- sub periosteal hematomas - joints = hemarthrosis = secondary OA
- Retrobulbar hematomas
2) Skeletal changes
- Poor quality of osteoid matrix = bowing legs
- shortening of alveoli = tooth loss
- protrusion ribs and sternum - pigeon chest
- depression of the sternum
3) Would healing
- delayed and takes longer
- Vitamin C is administered post surgery to speeds up repair
Too much vitamin C can result in
elimination of vitamin C (1500 mg)
What regulates the amount of Vitamin C in the body?
Kidney
What is the normal amount of vitamin C
60 mg