Pasteurella multocida

Question 1

specifics

Answer 1

gram -ve, obligate symbiotic, little resistant
type A- mucoid –> capsule and hyaluronic acid
obligate path- septicemia in bovine, birds, rabbits
faculative path- rhinitis, pneumonia in pig, bovine, rabbits

Question 2

poutry cs

Answer 2

ducks most susceptible
fowl cholera- chicken and turkeys
hyperacute in birds septicemic due to cat bites
acute- sudden death
chronic- chicken- sneezing, nose excretion, edema head

Question 3

virulence factors

Answer 3

cell wall 
lps 
iron aquisition by sidephores 
adhesins
capsule
toxin

Question 4

virulence factor- toxin

Answer 4

RTX- repeats in toxin - leukotoxin and hemolysis - impairs pulmonary macrophages, inflammation- tissue destruction
Rho activating toxin- pasteurella multocida toxin- PMT
dermonecrotic toxin- DMT
hyaloronidase
neuramidase

Question 5

prev

Answer 5

wound dysinfection
AB with fever, stab wound, sx, risk group

biting wound in humans- migrate to regional lymph nodes–> bacteremia/tissue localization