Francisella spp Flashcards
1
Q
specifics
A
gram -ve small pleomorphic coccoid rod non motile obligate aerobic very fastidious growth (rich media- chocolate agar, thayer martic agar
2
Q
F.tularensis CS
A
rare disease in animals
symptoms rarely seen
humans- type A is virulent, type b- mild
3
Q
mode of transmission
A
ulceroglandular glandular oculoglandular oro-pharyngeqal respiratory typhoid
4
Q
spread
A
NA- tularenesis, EU- holaritica, asia- mediasiatica
5
Q
epidemiology
A
reservoir - lagomorphs
transmission- ticks, mosquitos, flies, contaminated water, prey ingestion
human infection- wildlife, inhalation, insect bites
6
Q
pathogenesis
A
systemic- organ failure
faculative intracellular- macrophages
7
Q
dx
A
isolate bsl3
serology
PCR, RT PCR
