Pastest Flashcards

1
Q

What is Freidrich’s ataxia?

A

Autosomal recessive condition of childhood - degeneration of dorsal root ganglion cells , loss of myelinated peripheral nerve fibres & degenration of dorsal columns

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2
Q

What cardiac features are associated with Friedrich’s ataxia?

A

T wave inversion

Ventricular hypertrophy

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3
Q

Why is L-dopa given with carbidopa?

A

Carbidopa doesn’t cross BB and stop conversion of L-dopa to dopamine in peripheral circulation reducing side effects (nausea, vomiting hypotension)

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4
Q

What type of drug is Entacarpone?

A

COMT inhibitor

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5
Q

What preexisting conditions can increase the risk of haematogenous spread of infection to the brain?

A

Bronchiectasis
Congenital cyanotic heart disease
Acute endocarditis

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6
Q

Which vessel is most commonly affected by CVA?

A

Middle cerebral artery

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7
Q

Where does the middle cerebral artery supply?

A

Outer convex brain surface & lateral aspect of temporal lobe

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