Part III intro Flashcards
Exercise as a metabolism regulator:
Obeys the need for increased energy
Return to resting state metabolism is delayed after exercise. This is known as:
EPOC
Metabolism changes in organs other than skeletal muscle. Such as:
Liver, adipose tissue (beige adipose)
Chronic exercise changes the metabolic profile of individuals when:
Exercising AND at rest
Exercise parameters are:
Type (endurance, sprint)
Intensity (%VO2max)
Duration (acute, chronic)
Chronic exercise leads to _____ in metabolism
Adaptations
What is allosteric regulation?
The binding of a compound whose concentration increases with exercise to a site on an enzyme distinct from the active site
The binding of a compound whose concentration increases with exercise to a site on an enzyme distinct from the active site is known as:
Allosteric regulation
Allosteric regulation is:
Instantaneous
Precipitously reversible
What is Feedback inhibition?
A common inhibitor of rate-limiting enzymes is the product of the pathway
Enzyme activity can be controlled by reversible covalent addition of chemical groups. This is known as:
Covalent modification
Covalent modification occurs within:
Seconds
What do kinases do?
Add phosphates
What do phosphatases do?
Remove phosphates
Chronic adaptations lead to ____. It is long lived but the slowest, taking ___.
Changing enzyme concentration
Hours
An example of changing the substrate concentration would be:
This speeds up their catabolism
Increased glucose and fatty acid transport into skeletal muscles
