part 9 Flashcards

1
Q

bacteriostatic inhibitors of protein synthesis

A

tetracyclines

macrolides

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2
Q

What do tetracyclines end in?

A

-cycline

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3
Q

What are some adverse effects of tetracyclines?

A
  • tooth discoloration
  • diarrhea
  • should not be given with food
  • contraindicated with renal impairment
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4
Q

What are the therapeutic uses of tetracyclines?

A
  • infectious diseases
  • acne
  • peptic ulcer disease
  • periodontal disease
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5
Q

How are tetracyclines eliminated?

A

kidney and liver

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6
Q

What are the adverse effects of tetracyclines?

A
  • GI irritation
  • effects on bones and teeth (kids)
  • superinfection (because tetracyclines are broad spectrum)
  • hepatotoxicity
  • renal toxicity
  • photosensitivity
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7
Q

What should tetracyclines not be administered with?

A
  • calcium supplements
  • milk products
  • iron supplements
  • magnesium containing laxatives
  • most antacids (because they have magnesium and aluminum)
  • administer 1 hour before or 2 hours after “chelating” agents (these are the things listed above
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8
Q

What are the major precaution for tetracyclines?

A
  • can be toxic for pt’s with kidney disease
  • tooth discoloration (do not give to kids with baby teeth or pregnant/breastfeeding women
  • life threatening diarrhea
  • caution with liver damage
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