part 14

Question 1

Fungi infections can be divided into what two categories?

Answer 1

superficial mycoses

systemic mycoses

Question 2

Sysytemic mycoses can be divided into what 2 categories?

Answer 2

opportunistic (the person provides opportunity for disease) and nonopportunistic (caused by external vector)

Question 3

is the class and member for antifungal drugs?

Answer 3

polyene antibiotic

amphotericin B

Question 4

What is the drug of choice for systemic mycosis?

Answer 4

-broad spectrum
polyene antibiotic
amphotericin B

Question 5

this drug is highly toxic and may be associated with dleirium, hypotension, hypertension, wheezing, and hypoxia

Answer 5

polyene antibiotic

amphotericin B

Question 6

Since polyene antibiotic amphotericin B is infused IV what do we need to watch?

Answer 6

• kidney function every 3-4 days

- watch I&O’s

Question 7

How long is the treatment for polyene antibiotic

amphotericin B?

Answer 7

-6-8 weeks or up to 3-4 months

Question 8

This is a boad spectrum antifungal, lower toxicity and can be given po. can cause cardiac suppression and liver injury.

Answer 8

Azoles

Question 9

This treats herpes and varicella-zoster. Can be given PO or IV, serious side effects are uncommon.

Answer 9

antiviral: acyclovir

Question 10

Are antibiotics effective against the flu?

Answer 10

no

Question 11

What is the neuraminidase inhibitor oseltamivir?

Answer 11

tamiflu

Question 12

When does tamiflu need to be administered in order to be effective?

Answer 12

no later than 2 days after symptom onset or sooner

Question 13

What are some of the side effects of tamiflu?

Answer 13

N, V, anaphylaxis, serious skin reaction (epidermal necrolysis, erythema multiforme, steven-johnson syndrome)