Part 6 Flashcards

1
Q

At birth, there is increased blood flow through the?

A

Lungs and Liver

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2
Q

At birth, pulmonary vascular resistance?

A

Decreases

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3
Q

At birth there is loss of blood flow through the?

A

Placenta

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4
Q

Loss of blood flow through the placenta doubles the?

A

Systemic Vascular Resistance

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5
Q

At birth, there is closure of?

A

Foramen Ovale
Ductus Arteriosis
Ductus Venosus

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6
Q

Closure of foramen ovale is due to reversal of pressure gradient between?

A

R and L atrium

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7
Q

Reversal of flow from aorta to pulmonary artery, and increased oxygen levels cause constriction of smooth muscle causes closure of?

A

Ductus Arteriosis

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8
Q

It’s unknown why ductus venosus closes, but it allows portal blood to?

A

Perfuse Liver Sinuses

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9
Q

In fetal circulation, the R and L ventricle pump in parallel into the?

A

Aorta

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10
Q

In fetal circulation there is very little?

A

Pulmonary Blood Flow

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11
Q

In fetal circulation there is low pressure in the aorta due to low TPR because of?

A

Placenta-Umbillical Arteries

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12
Q

In fetal circulation, blood returning from the placenta via the umbilical veins bypass liver and flow directly into?

A

IVC via Ductus Venosus

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13
Q

In a fetus there exists 2 right to left shunts for blood to bypass?

A

Lungs

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14
Q

Foramen ovale shunts most blood returning to the heart from the?

A

IVC to the L atrium

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15
Q

Ductus Arteriosis shunts most blood returning to the heart from the?

A

SVC to the Aorta

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16
Q

What’s the greatest stress on the cardiovascular system?

A

Exercise

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17
Q

Sympathetic nervous system orchestrates many of the changes associated with?

A

Exercise

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18
Q

With exercise what in increase 5-6 fold?

A

Cardiac Output

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19
Q

During exercise, blood flow is shifted primarily from organs to?

A

Active skeletal muscle

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20
Q

During exercise there is cerebral cortical activation of the?

A

Sympathetic Nervous System

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21
Q

The SNS will cause vasoconstriction of arterioles to decrease?

A

Flow to non active tissues (viscera)

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22
Q

The SNS will cause vasoconstriction of veins to increase MCFP which increases?

A

Venous Return

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23
Q

The SNS will stimulate the heart by increasing HR and SV which ultimately increases?

A

Cardiac Output

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24
Q

During exercise TPR decreases due to?

A

Vasodilation in active muscle

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25
During exercise increase O2 uptake decreases VO2 which increases?
AVO2 Difference
26
SNS stimulation is due to?
Cerebral Cortex Stimulation
27
Reflex signals from active joint proprioceptors and muscles as well as local chemoreceptor signals originating in the active muscle will stimulate?
SNS
28
SNS will induce local metabolic vasodilation at the?
Heart
29
SNS stimulation of pre-capillary resistance vessels decreases?
Blood Flow
30
SNS stimulation of veins causes constriction which mobilizes blood out of veins and increases?
Venous Return
31
SNS stimulation of vascular smooth muscle in walls of arteries help maintain?
Slightly increased BP during exercise
32
SNS indirectly induces local vasodilation of the heart by?
Increasing cardiac muscle contractibility | Promoting the release of local vasodilators
33
SNS stimulation in the brain induces a weak constrictor response that?
Doesn't limit blood flow
34
SNS stimulation in the lungs induces a mild vasoconstriction that?
Doesn't limit blood flow
35
During exercise increased systolic BP is due to increased cardiac output which ?
Decreases TPR
36
During exercise increased diastolic BP is only?
Slightly
37
During exercise pulse pressure is?
Increased
38
SNS constricts veins when there is an increase venous return during?
Exercise
39
Intermittent skeletal muscle activity coupled with | one way valves in veins is known as?
Venous Pump
40
Venous pump primarily occurs in?
Lower Extremities
41
Increased venous return during exercise will increase?
Frequency & Depth of respiration
42
Increased frequency & depth of respiration will increase?
Cyclic negative thoracic pressure
43
Increased blood flow to the active muscle is NOT mediated by the SNS but by the local release of tissue metabolites in response to?
Increase in metabolism
44
What are local vasodilators?
``` Adenosine CO2 K+ Histamine Lactic acid ```
45
Resting cardiac output is?
5.9 L/min
46
Blood flow during exercise is?
24 L/min
47
During exercise what is decreased?
TPR | SV increases to a point and then may decrease
48
The maximum volume of oxygen that one can take up from the lungs and deliver to the tissues/minute is?
VO2 Maximum
49
What can range from 1.5 L/min in a cardiac patient to 3.0 L/min in a sedentary man to 6.0 L/min or greater in an endurance athlete?
VO2 Max
50
VO2 max is the function of?
CO and AVO2 difference
51
``` If energy (E) demands of exercise cannot be met by oxidative phosphorylation what happens? ```
O2 debt occurs
52
After completion of exercise, respiration remains | elevated to repay the O2 debt of about?
11.5 L
53
Extra O2 is used to?
Restore metabolite levels | Metabolize lactate generated by glycolysis
54
E consumed during exercise – that E supplied by oxidative metabolism is equal to?
O2 Debt
55
The phosphocreatine-creatine system uses what?
ATP | Creatine Phosphate
56
The phosphocreatine-creatine system occurs during exercise when?
8-10 seconds after starting exercise
57
The glycogen-lactic acid system uses what?
Glycolysis
58
The glycogen-lactic acid system occurs during exercise when?
1.3-1.6 min after starting exercise
59
During glycolysis, glycogen is spilt into glucose which makes 2 pyruvate which is used as?
Energy
60
The aerobic system is unlimited with?
O2 and Nutrients
61
The aerobic system oxidizes fatty acids which produces?
Energy
62
The aerobic system occurs in the?
Mitochondria with sufficient O2