Part 1 Flashcards
Delivering adequate oxygen & nutrients to the systemic tissues and removing carbon dioxide and other waste products from the systemic tissues is the main function of?
Systemic Circulation
Systemic circulation serves as a conduit for transport of hormones and other substances and it allows these substances to?
Potentially act at a distant site from their production
What are designed to carry blood under high pressure out to the tissue beds?
Systemic Arteries
What act as control valves to regulate local flow?
Arterioles and Pre-capillary Sphincters
Capillaries (one cell layer thick) exchange between?
Tissue (cells) and blood
Venules collect blood from?
Capillaries
What returns blood to the heart/dynamic storage?
Systemic Veins
Blood flow is proportional to?
Metabolic Demand
Cardiac output is controlled by?
Local Tissue Flow
What is independent of local flow or cardiac output?
Arterial Pressure Control
What are the components of vessels?
- Endothelium ( 1 layer in all vessels)
- Elastic Tissue
- Smooth Muscle
- Fibrous Tissue
The relative composition of the aorta is?
1 >3 >2
The relative composition of a typical artery is?
2 > 1 > 3
The relative composition of a vein is?
1=2=3
The relative composition of a capillary is?
Only endothelium
What is the volume of blood that passes a certain point per unit of time (e.g.. ml/min) ?
Flow (F)
At a given flow, the velocity is inversely proportional to the?
Total cross sectional area
F = velocity x cross sectional area
Flow is directly proportional to the change in pressure and inversely proportional to?
Resistance (R)
F = change in pressure/R
What is the driving force of blood?
Pressure Gradient
Pressure gradient is the difference in?
Pressure between two points
Pressure gradient is proportional to?
Flow
At a given flow, the greater the drop in pressure in a segment or compartment the greater the?
Resistance to flow
The greatest resistance to flow occurs in the?
Pre-capillary resistance vessels (arterioles, metaarterioles, precapillary sphincters)
Resistance equals?
8nl/pi r^4
n=viscosity
l=length of vessel
r=radius