Part 4 Gyn. Infections Flashcards
What are the TORCH infections?
Toxoplasmosis Other (syphilis, VZV, parvovirus B19) Rubella CMV HSV
What is the host for Toxoplasmosis?
Cat feces or raw meat
If an infant is infected with a Protozoan Parasite, what is the likely organsim?
Toxoplasmosis
What will be the symptoms of the fetus if they do not expire before birth with Toxoplasmosis?
CNS calcifications
Chorioretinitis
What screen is done for detecting Toxoplasmosis?
serology with:
IgG
IgM
Early Congenital Syphilis occurs before the child is 2. What are the signs?
SNUFFLES - mucus membrane involvement
Rash on palms/soles/genitals
Late Congenital Syphilis occurs after > 2 years old. What are the bone manifestations?
Saber shins - bowing tibia
Central tooth notching
Frontal bossing of the forehead
Which child is more likely to have signs of neurosyphilis with hearing loss
– 1 year old or 5 years old?
5 – late congenital syphilis = hearing loss and neurosyphilis
neurosyphillis: sensorineural hearing loss (8th nerve), gumma formation
If the child is infected with Varicella Zoster in utero, what are the signs? Congenital varicella syndrome
Limb hypoplasia
cicatrical Skin lesions
how do you treat an infant who has contracted varicella from a maternal peripartum infection either with varicella or with herpes zoster?
acyclovir
If a child is infected with Parvovirus B19 as a child, what is the sign?
Slapped cheeks
If a fetus is infected with Parvovirus B19 IN UTERO, what may occur?
The virus attacks RBCs —> anemia —> HYDROPS FETALIS
What are the 3 signs of Congenital Rubella?
sensorineural Hearing loss
Cataracts
Heart disease
What are the signs that a child has Rubella?
URI, head to toe rash, fever, LAD
What precedes the head to toe rash with Rubella?
Soft palate petechiae
what is the most common congenital viral infection?
CMV
CMV infection can often be ______
Asymptomatic
“owl’s eye inclusion”
CMV
CMV causes?
Sensorineural hearing loss
If a child has Sensorineural hearing loss, what likely infection did they get?
CMV
How is an infant infected with HSV?
DURING BIRTH - contact
Group B Strep. Agalactiae can cause what 3 things to the infant?
Sepsis
Meningitis
Pneumonia
Attributes of Group B strep. Agalactiae?
Gram (+) cocci in chains
BETA - HEMOLYTIC
lancefiled group B
What is the virulence factor for Group B strep. Agalactiae?
Capsule prevents phagocytosis
What is the treatment for Group B strep during labor?
DURING LABOR = Penicillin G or Ampicillin
How does post partum endometritis present?
fever, uterine tenderness, tachycardia, midline lower abdominal pain
what are the risk factors of post partum endometritis?
colonization with GBS, c-section
how do you treat post partum endometritis?
treat empirically for target organisms (polymicrobial)
gentamicin PLUS clindamycin
or
ampicillin/ sulbactam
how do you treat mastitis?
MSSA: amoxicillin/clavulanate
MRSE: TMPSMX
