Epithelial Ovarian Tumors Flashcards
Epithelial ovarian tumors are the most common type. At what age do they present?
20+
What are the 5 subtypes of Epithelial Ovarian tumors?
- Serous
- Mucinous
- Endometrioid
- Clear cell
- Transitional cell
What are the 5 subtypes of Epithelial Ovarian tumors?
- Serous
- Mucinous
- Endometrioid
- Clear cell
- Transitional cell
What are the 3 classifications of Epithelial Ovarian tumors?
Benign
Borderline
Malignant
A cystic benign epithelial tumor
Cystadenoma
A cystic and fibrous benign epithelial tumor
Cystadenofibroma
A fibrous benign epithelial tumor
Adenofibroma
Serous Epithelial tumors can be what 2 grades?
Low grade
High grade
Low grade serous epithelial tumor
Cystic with tubal epithelium and papillary growth
High grade serous epithelial tumor
Solid tumor with atypia
A High grade serous epithelial tumor is associated with what mutations?
TP53
BRCA1 and 2
What type of epithelium do Mucinous Epithelial tumors have?
Columnar
Mucinous Epithelial tumors are unilateral or bilateral?
Unilateral
What mutation is associated with Mucinous Epithelial tumors?
KRAS
Unilateral cystic lesion with columnar epithelium
Mucinous tumor
What is often a precursor for an Endometrioid Epithelial tumor?
Endometriosis
Most Endometrioid and Clear cell Epithelial tumors are _____
Carcinomas
What histo attributes are present with Clear Cell Epithelial tumors?
Large epithelial cells with clear cytoplasm
Transitional cell tumor alternate name
Brenner tumor
What type of epithelium is present with a Brenner tumor?
Urothelial type transitional epithelium
Brenner tumors are usually malignant or benign?
Benign
Urothelial type transitional epithelium
Brenner tumor
Large cells with clear cytoplasm
Clear cell tumor
KRAS mutations
Mucinous tumor
P53, BRCA 1 and 2 mutations
Serous tumor (high grade solid tumor)
