Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Dosage Forms > PART 4 > Flashcards

PART 4 Flashcards

1
Q

“Capsula” means ___.

A

small container

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Solid dosage forms in which the medicinal agents and/or inert substances are enclosed in a small gelatin shell.

A

Capsules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Gelatin is a product of partial ____ of collagen obtained from the skin, white connective tissue, and bones of animals.

A

Hydrolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Type A Gelatin is derived from ___ by acid processing.

A

Pork skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Type B Gelatin is obtained from ___ by alkaline processing.

A

Bones and animal skins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Type of capsule used by community pharmacists in extemporaneous compounding of prescriptions. It is also commonly employed in clinical drug trials to compare investigational drug to another drug or a placebo.

A

Hard gelatin capsules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Hard gelatin capsules are also called ___ or ___.

A

Dry-filled capsule or 2-piece capsule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Gelatin contain ___ to ___ of moisture

A

13% to 16%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Capsule shell sizes for hard gelatin capsules

A

000 (largest)
00
1
2
3
4
5 (smallest)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Opaquant used in hard gelatin capsules

A

Titanium dioxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Component of hard gelatin capsules that prevents decomposition

A

0.15% Sulfur dioxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

It is used to produce the proper capsule fill volume and improve content uniformity.

A

Diluents/Fillers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Assist break-up and distribution of the capsule contents in the stomach.

A

Disintegrants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Improve flow properties of powder mixture

A

Lubricants or glidants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Facilitates wetting of powder by the GI fluids

A

Surface active agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Sodium lauryl sulfate

A

Surface active agents

17
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Fumed silicon dioxide
Magnesium stearate (!!!)
Calcium stearate
Stearic acid
Talc

A

Lubricants or glidants

18
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Pregelatinized starch
Croscarmellose
Sodium starch glycolate

A

Disintegrants

19
Q

IDENTIFY THE COMPONENT OF HARD GELATIN CAPSULE DESCRIBED.

Lactose
Microcrystalline cellulose
Starch

A

Diluents or Fillers

20
Q

Capsule filling method used in small scale production.

A

Punch method

21
Q

The process by which the inner surface of the cap is lightly coated with a warm gelatin solution. For large-scale, heat welding or liquid welding is employed.

A

Capsule sealing

22
Q

What is the moisture content of soft gelatin capsule?

A

6-10%

23
Q

It is used to render soft gelatin capsules elastic or plastic-like.

A

Plasticizer (Glycerin or polyhydric alcohol such as sorbitol)

24
Q

API: Plasticizer ratio

A

1:0.08

25
Q

Preservatives added to prevent fungal growth in soft gelatin capsules

A

Methylparaben or propylparaben

26
Q

METHODS OF PREPARING SGC

It is a continuous process wherein two plasticized gelatin ribbons are continuously and simultaneously fed with liquid or paste fill between the rollers of the rotary die mechanism.

A

Rotary Die Process

27
Q

Gelatin ribbons are fed between a set of vertical dies that continually open and close to form rows of packets in gelatin ribbons.

A

Reciprocating Die Process

28
Q

METHODS OF PREPARING SGC

A warm sheet of plain or colored gelatin is placed on the bottom plate of the mold, and the medication-containing liquid is evenly poured on it.

A

Plate Process

29
Q

Three examples of desiccants used for capsules

A

Silica gel
Clay
Activated charcoal

30
Q

Hermetically sealed capsules that encapsulate liquids, suspensions, pasty materials, or dry powders

A

Soft gelatin capsules

Dosage Forms (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions