PART 2

Question 1

___ is a mixture of finely divided drugs and/or chemicals used internally or externally.

Answer 1

Powder

Question 2

The Latin name for powder is ___.

Answer 2

Pulvis

Question 3

True or False:

Powders have good chemical stability and are dispersed rapidly due to their small particle size.

Answer 3

True

Question 4

True or False:

Powders are difficult to administer and not suitable for dispensing.

Answer 4

True

Question 5

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 80 sieve. There is no limit to greater fineness.

Answer 5

No. 80
Very fine

Question 6

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 60 sieve and NMT 40% through a # 100 sieve.

Answer 6

No. 60
Fine

Question 7

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 40 sieve and NMT 40% through a # 80 sieve.

Answer 7

No. 40
Moderately coarse

Question 8

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 20 sieve and NMT 20% through a # 60 sieve.

Answer 8

No. 8
Very coarse

Question 9

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 20 sieve and NMT 40% through a # 60 sieve.

Answer 9

No. 20
Coarse

Question 10

It is the process of reducing particle size.

Answer 10

Comminution

Question 11

___ is the use of mortar and pestle for small-scale reduction of particle size.

Answer 11

Trituration

Question 12

Triturating the powder with a small amount of liquid wherein the substance is insoluble.

Answer 12

Levigation

Question 13

This process is used in the preparation of ointments and suspensions.

Answer 13

Levigation

Question 14

The liquid that is used in levigation that is viscous in nature
with a low surface tension to easily wet the solid
particles.

Answer 14

Levigating agent (mineral oil or glycerin)

Question 15

This process is applied to substances which are gummy or resist grinding.

Answer 15

Pulverization by intervention

Question 16

It uses a solvent in which that material is soluble (volatile solvent such as alcohol or acetone) that is easily removed (evaporated) after pulverization.

Answer 16

Pulverization by intervention

Question 17

Examples are camphor + alcohol and iodine crystals + ether.

Answer 17

Pulverization by intervention

Question 18

A large-scale comminuting machine with a product containment system.

Answer 18

FitzMill Comminutor

Question 19

It is useful for solid substances that liquefy or form eutectic mixtures (i.e., mixtures that melt at a lower temperature than any of their ingredients) when in close, prolonged contact with one another because little compression or compaction results.

Answer 19

Spatulation

Question 20

Phenol, camphor, menthol, thymol, aspirin, and phenyl salicylate are examples of ___ mixtures.

Answer 20

Eutectic

Question 21

Four methods for mixing/blending powders

Answer 21

SSTT

1. Spatulation
2. Sifting
3. Trituration
4. Tumbling

Question 22

Powders are mixed by passing them through sifters similar to those used to sift flour.

Answer 22

Sifting

Question 23

The process of mixing powders in a large container rotated by a motorized process.

Answer 23

Tumbling

Question 24

Type of mortar for trituration that is smooth, nonporous, and good for simple mixing. It can be used for solutions/suspensions.

Answer 24

Glass mortar

Question 25

Type of mortar for crystals

Answer 25

Wedgewood mortar

Question 26

Type of mortar for soft, aggregate crystals and semi-solids.

Answer 26

Porcelain or ceramic mortar

Question 27

It is the type of mortar that is most commonly used.

Answer 27

Porcelain or ceramic mortar

Question 28

It is the method of mixing/blending potent substances with a large amount of diluent.

Answer 28

Geometric dilution

Question 29

Packaging for oral bulk powders

Answer 29

Wide-mouthed glass

Question 30

Packaging for topical bulk powders

Answer 30

Perforated or sifter cans

Question 31

Powders that are taken by mixing with water, usually antacids or laxatives.

Answer 31

Oral powders

Question 32

Powders dissolved in warm water for vaginal use

Answer 32

Douche powders

Question 33

Medicated or non-medicated powders for external application to the skin, locally applied, and non-toxic.

Answer 33

Dusting powders

Question 34

Substances used with a toothbrush for the purpose of cleaning the accessible surface of the teeth.

Answer 34

Dentrifices

Question 35

Generally contains soap or detergent, mild abrasive, and anti-cariogenic agent (tending to prevent tooth decay).

Answer 35

Dentrifices

Question 36

Finely divided powders that are intended to be applied in a body cavity, such as the ears, nose, vagina, tooth socket, or throat with the use of a bulb applicator (insufflator)

Answer 36

Insufflation

Question 37

Moisture-activated adherent, ethylene oxide polymer with HMW, forms a viscous mucoadhesive gel when exposed to moisture

Answer 37

Polyox

Question 38

Latin name for divided powders

Answer 38

Chartulae or chartula

Question 39

Dispensed in the form of individual doses and generally dispensed in papers, properly folded

Answer 39

Divided powders

Question 40

Method of dividing powders that uses an analytical balance (more accurate)

Answer 40

Individual weighing

Question 41

Method of dividing powders that uses a pill tile (estimated)

Answer 41

Block and divide method

Question 42

TYPES OF PAPER It has no moisture properties.

Answer 42

Bond paper

Question 43

TYPES OF PAPER ___ is a thin, semi-opaque, moisture-resistant paper (limited barrier against moisture).

Answer 43

Vegetable parchment

Question 44

TYPES OF PAPER A glazed, transparent moisture resistant paper that has no protection for photodegradation and is used for volatile materials.

Answer 44

Glassine paper

Question 45

TYPES OF PAPER Transparent waterproof paper for hygroscopic, deliquescent, and volatile drugs

Answer 45

Wax paper

Question 46

___ powders will absorb moisture from the air.

Answer 46

Hygroscopic

Question 47

___ powders will absorb moisture from the air to the extent that they will partially or wholly liquefy.

Answer 47

Deliquescent

Question 48

___ powders lose water through evaporation when exposed to air. It gives off water of crystallization.

Answer 48

Efflorescent

Question 49

TYPES OF POWDERS ___ powders must pass through at least a No. 100-mesh sieve to minimize skin irritation.

Answer 49

Topical

Question 50

Four components of topical powders

Answer 50

1. Base or vehicle 2. Adherent (Stearates) 3. Active ingredient 4. Aromatic material

Question 51

___ and ___ may be used when only a limited barrier against moisture is necessary.

Answer 51

Glassine Vegetable parchment

Question 52

___ and ___ are best protected with waxed paper that is double wrapped and covered with a bond paper to improve the appearance.

Answer 52

Hygroscopic Volatile drugs

Question 53

Powders containing neither volatile components nor ingredients adversely affected by air or moisture are usually wrapped in ___.

Answer 53

White bond paper

Question 54

Medicated powders for ___ use are dusted on the affected area from a sifter-type container or powder aerosol.

Answer 54

External

Question 55

___ powders make use of dry powder inhaler/metered dose inhaler to deliver micronized particles of medication in metered quantities.

Answer 55

Aerosol

Question 56

Aerosol powders are ___ in diameter.

Answer 56

1 to 6 𝜇m

Question 57

Medicated powders for internal use are administered ___ after mixing with water.

Answer 57

Orally

Question 58

MEDICATED POWDERS Laxatives for local internal use are administered via ___.

Answer 58

Inhalation

Question 59

MEDICATED POWDERS ___ for systemic internal use are administered via inhalation.

Answer 59

Analgesics

Question 60

MEDICATED POWDERS Powder for reconstitution with a liquid solvent or vehicle (ROA)

Answer 60

Oral Injection Vaginal douche

Question 61

Inert propellants and diluents