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Dosage Forms > PART 2 > Flashcards

PART 2 Flashcards

1
Q

___ is a mixture of finely divided drugs and/or chemicals used internally or externally.

A

Powder

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2
Q

The Latin name for powder is ___.

A

Pulvis

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3
Q

True or False:

Powders have good chemical stability and are dispersed rapidly due to their small particle size.

A

True

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4
Q

True or False:

Powders are difficult to administer and not suitable for dispensing.

A

True

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5
Q

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 80 sieve. There is no limit to greater fineness.

A

No. 80
Very fine

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6
Q

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 60 sieve and NMT 40% through a # 100 sieve.

A

No. 60
Fine

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7
Q

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 40 sieve and NMT 40% through a # 80 sieve.

A

No. 40
Moderately coarse

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8
Q

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 20 sieve and NMT 20% through a # 60 sieve.

A

No. 8
Very coarse

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9
Q

PARTICLE SIZE: Identify the powder number and descriptive term.

All particles pass through a # 20 sieve and NMT 40% through a # 60 sieve.

A

No. 20
Coarse

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10
Q

It is the process of reducing particle size.

A

Comminution

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11
Q

___ is the use of mortar and pestle for small-scale reduction of particle size.

A

Trituration

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12
Q

Triturating the powder with a small amount of liquid wherein the substance is insoluble.

A

Levigation

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13
Q

This process is used in the preparation of ointments and suspensions.

A

Levigation

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14
Q

The liquid that is used in levigation that is viscous in nature
with a low surface tension to easily wet the solid
particles.

A

Levigating agent (mineral oil or glycerin)

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15
Q

This process is applied to substances which are gummy or resist grinding.

A

Pulverization by intervention

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16
Q

It uses a solvent in which that material is soluble (volatile solvent such as alcohol or acetone) that is easily removed (evaporated) after pulverization.

A

Pulverization by intervention

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17
Q

Examples are camphor + alcohol and iodine crystals + ether.

A

Pulverization by intervention

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18
Q

A large-scale comminuting machine with a product containment system.

A

FitzMill Comminutor

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19
Q

It is useful for solid substances that liquefy or form eutectic mixtures (i.e., mixtures that melt at a lower temperature than any of their ingredients) when in close, prolonged contact with one another because little compression or compaction results.

A

Spatulation

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20
Q

Phenol, camphor, menthol, thymol, aspirin, and phenyl salicylate are examples of ___ mixtures.

A

Eutectic

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21
Q

Four methods for mixing/blending powders

A

SSTT

  1. Spatulation
  2. Sifting
  3. Trituration
  4. Tumbling
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22
Q

Powders are mixed by passing them through sifters similar to those used to sift flour.

A

Sifting

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23
Q

The process of mixing powders in a large container rotated by a motorized process.

A

Tumbling

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24
Q

Type of mortar for trituration that is smooth, nonporous, and good for simple mixing. It can be used for solutions/suspensions.

A

Glass mortar

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25
Q

Type of mortar for crystals

A

Wedgewood mortar

26
Q

Type of mortar for soft, aggregate crystals and semi-solids.

A

Porcelain or ceramic mortar

27
Q

It is the type of mortar that is most commonly used.

A

Porcelain or ceramic mortar

28
Q

It is the method of mixing/blending potent substances with a large amount of diluent.

A

Geometric dilution

29
Q

Packaging for oral bulk powders

A

Wide-mouthed glass

30
Q

Packaging for topical bulk powders

A

Perforated or sifter cans

31
Q

Powders that are taken by mixing with water, usually antacids or laxatives.

A

Oral powders

32
Q

Powders dissolved in warm water for vaginal use

A

Douche powders

33
Q

Medicated or non-medicated powders for external application to the skin, locally applied, and non-toxic.

A

Dusting powders

34
Q

Substances used with a toothbrush for the purpose of cleaning the accessible surface of the teeth.

A

Dentrifices

35
Q

Generally contains soap or detergent, mild abrasive, and anti-cariogenic agent (tending to prevent tooth decay).

A

Dentrifices

36
Q

Finely divided powders that are intended to be applied in a body cavity, such as the ears, nose, vagina, tooth socket, or throat with the use of a bulb applicator (insufflator)

A

Insufflation

37
Q

Moisture-activated adherent, ethylene oxide polymer with HMW, forms a viscous mucoadhesive gel when exposed to moisture

A

Polyox

38
Q

Latin name for divided powders

A

Chartulae or chartula

39
Q

Dispensed in the form of individual doses and generally dispensed in papers, properly folded

A

Divided powders

40
Q

Method of dividing powders that uses an analytical balance (more accurate)

A

Individual weighing

41
Q

Method of dividing powders that uses a pill tile (estimated)

A

Block and divide method

42
Q

TYPES OF PAPER

It has no moisture properties.

A

Bond paper

43
Q

TYPES OF PAPER

___ is a thin, semi-opaque, moisture-resistant paper (limited barrier against moisture).

A

Vegetable parchment

44
Q

TYPES OF PAPER

A glazed, transparent moisture resistant paper that has no protection for photodegradation and is used for volatile materials.

A

Glassine paper

45
Q

TYPES OF PAPER

Transparent waterproof paper for hygroscopic, deliquescent, and volatile drugs

A

Wax paper

46
Q

___ powders will absorb moisture from the air.

A

Hygroscopic

47
Q

___ powders will absorb moisture from the air to the extent that they will partially or wholly liquefy.

A

Deliquescent

48
Q

___ powders lose water through evaporation when exposed to air. It gives off water of crystallization.

A

Efflorescent

49
Q

TYPES OF POWDERS

___ powders must pass through at least a No. 100-mesh sieve to minimize skin irritation.

A

Topical

50
Q

Four components of topical powders

A
  1. Base or vehicle
  2. Adherent (Stearates)
  3. Active ingredient
  4. Aromatic material
51
Q

___ and ___ may be used when only a limited barrier against moisture is necessary.

A

Glassine
Vegetable parchment

52
Q

___ and ___ are best protected with
waxed paper that is double wrapped and covered with
a bond paper to improve the appearance.

A

Hygroscopic
Volatile drugs

53
Q

Powders containing neither volatile components nor
ingredients adversely affected by air or moisture are
usually wrapped in ___.

A

White bond paper

54
Q

Medicated powders for ___ use are dusted on the affected area from a sifter-type container or powder aerosol.

A

External

55
Q

___ powders make use of dry powder inhaler/metered dose inhaler to deliver micronized particles of medication in metered quantities.

A

Aerosol

56
Q

Aerosol powders are ___ in diameter.

A

1 to 6 𝜇m

57
Q

Medicated powders for internal use are administered ___ after mixing with water.

A

Orally

58
Q

MEDICATED POWDERS

Laxatives for local internal use are administered via ___.

A

Inhalation

59
Q

MEDICATED POWDERS

___ for systemic internal use are administered via inhalation.

A

Analgesics

60
Q

MEDICATED POWDERS

Powder for reconstitution with a liquid solvent or
vehicle (ROA)

A

Oral
Injection
Vaginal douche

61
Q

Inert propellants and diluents

A

Dosage Forms (6 decks)

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