PART 2 CRUDE DRUGS & WATER CONTENT

Question 1

Carbonization – aka ____

Answer 1

pyrolysis

Question 2

sample is prepared by
removing volatile matter using Bright red heat

Answer 2

Carbonization – aka pyrolysis

Question 3

This method is the most rapid,
requires only a small sample and
is specific for water

Answer 3

Method I - Karl Fischer
method

Question 4

The method involves titration of the sample
in reagent methanol with Karl Fischer
reagent

Answer 4

Method I - Karl Fischer
method

Question 5

Karl Fischer
reagent, which consists of

Answer 5

iodine, sulfur
dioxide, pyridine, and methanol.

Question 6

is specified for the
determination of moisture content of many
vegetable drugs

Answer 6

Method II – Azeotropic
Method

Question 7

The Azeotropic Method is specified for the
determination of moisture content of many
vegetable drugs containing __% or more of
moisture.

Answer 7

2

Question 8

mixture of liquids with constant
boiling point

Answer 8

AZEOTROPE

Question 9

Azeotropic disadvantage is the need for a large
amount of drug, from______ to ______must be used in order to secure a
volume of water that can be measured
conveniently without considerable error

Answer 9

fifty (50) to one hundred
(100) grams

Question 10

Water at Very Low
Concentration:

Answer 10

Dew Point Method

Question 11

Water at Extremely Low
Concentration

Answer 11

Electrolytic Hygrometric Method

Question 12

1 mL of of the reagent is equivalent to
approximately _ milligrams of water

Answer 12

5