[parkinsonisms]

Answer 1

Tremor
Rigidity/tone
Brady/hypokinesia

Answer 2

tremor at rest

Answer 3

pill-rolling

Answer 4

expressionless (hypomimesis)

Answer 5

decreased amplitude of movement

Answer 6

Neuroleptics

Answer 7

Metoclopramide (D-R antagonist)

Prochlorperazine (D-R2 antagonist)

Answer 8

Manganese

Copper (Wilson’s)

Answer 9

65

Answer 10

Mitochrondrial DNA dysfunction
degeneration of dopaminergic neurons in substantia nigra pars compacta
(associated with Lewy bodies)

Answer 11

5-10 years

Answer 12

Ropinirole

Pramipexole

Question 13

[PD]: For sudden ‘off’ freezing, what medical Tx (in ‘rescue-pen’ form) is used?

Answer 13

Apomorphine

Answer 14

reduced sense of smell
constipation
depression

Answer 15

poor emotional content of speech decoding

Answer 16

Freezing whilst walking

Answer 17

Selegiline

Rasagiline

Answer 18

COMT inhibitors

entacapone/tolcapone

Answer 19

hepatic complications

LFTs monitor

Answer 20

Benzhexol
Orphenadrine
(anticholinergics)

Answer 21

Confusion in elderly

Answer 22

Carbidopa

madopar/Sinemet

Answer 23

Disease progression

Drug SE

Answer 24

Domperidone

Answer 25

VIVID

Answer 26

progressive supra nuclear palsy

Answer 27

Multi system atrophy

Answer 28

Lewy body dementia

Answer 29

Cortico-basal degeneration

Answer 30

Vascular parkinsons

Answer 31

partly dopamine responsive

Answer 32

Ablation of sub-thalamic nucleus