[Multiple Sclerosis] Flashcards
Vit D
Unilateral optic neuritis
optic neuritis
Limbs numbness
Leg weakness
Diplopia/ataxia (brainstem/cerebellar involvement)
male
lesions disseminated in time and space unattributable to another cause
Brief period of visual disturbance, unexplained.
McDonald
Devic’s syndrome
aka neuromyelitis optica
Devics
peripheral (multiple and small)
Continuous and long
Anti-AQP4 (NMO-IgG: aka)
Stress reduction (reduced new lesions incidence)
Vit D
Methylprednisolone (for <3days)
2 (due to SE)
Alemtuzumab
Natalizumab
Oligoclonal IgG bands
More common the further away from the equator.
Worse at higher temperatures (bath/warm)
indicates optic nerve damage
IFN-1alpha
IFN-1beta
decreased central vision
pain on movement
heat (e.g. hot bath)
exercise
Gadolinium