[epilepsy] Flashcards

1
Q
A

T

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2
Q
A

Temporal Lobe

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3
Q
A

sore tongue due to severe tongue bite

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4
Q
A

cortex

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5
Q
A

cortical scarring

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6
Q
A

1 year

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7
Q
A

“you must contact the DVLA”

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8
Q
A

idiopathic

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9
Q
A

Partial

Primary generalised

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10
Q
A

Partial

The attack ONSET is key for Dx

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11
Q
A

A seizure with features referable to one part of one hemisphere

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12
Q
A

Simultaneous onset of electrical discharge throughout the cortex i.e. no localising features (at onset)

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13
Q
A

simple partial
complex partial
Partial with secondary generalisation

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14
Q
A
absence
tonic-clonic
myoclonic
atonic (akinetic)
infantile
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15
Q
A

temporal

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16
Q
A

awareness unimpaired
focal symptoms
post ictal symptoms usually absent

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17
Q
A

Awareness impaired
focal symptoms
post-ictal symptoms common

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18
Q
A
headache
confusion
sore tongue
myalgia
temporary weakness (can get in partial)
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19
Q
A

temporary weakness due to focal cortical seizure

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20
Q
A

temporal

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21
Q
A

Frontal

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22
Q
A

temporal

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23
Q
A

focal start (either simple/complex)
spreads to generalised
usually convulsive

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24
Q
A
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25
Q
A

generalised -absence

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26
Q
A

Loss of consciousness
limbs stiffen (tonic)
limbs jerk (clonic)
post-ictal confusion

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27
Q
A

sudden jerk of face/limb/trunk

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28
Q
A

sudden loss of tone (fall?)

29
Q
A

occipital

30
Q
A

frontal

31
Q
A

motor

32
Q
A

spreading motor seizure from a distal part of a limb to the ipsilateral face.
retained awareness

33
Q
A

frontal

Temporal

34
Q
A

brief unconscious behaviours

motor behaviours with no recollection

35
Q
A
jamais vu 
(strangely unfamiliar)
36
Q
A

temporal lobe

37
Q
A

temporal

38
Q
A

frontal retains awareness

39
Q
A

temporal

40
Q
A

temporal

41
Q
A

2

42
Q
A

Sodium valproate

Lamotrigine

43
Q
A

Sodium valproate
lamotrigine
ethosuximide

44
Q
A

Carbemazepine
oxcarbazepine

*worsen seizures)

45
Q
A

Carbamazepine
100mg/12hr intitial
increase by 200mg every 2weeks
max 1000mg

46
Q
A

Sodium valproate

lamotrigine

47
Q
A

Concurrently administer 1st and 2nd line and only withdraw 1st once established on 2nd line

48
Q
A

risk of recurrence following a 1st time unprovoked seizure

49
Q
A

MRI

50
Q
A

neurosurgical resection (70% seizure free)

51
Q
A

neurosurgical resection

Vagus nerve stimulation

52
Q
A

nocturnal seizure apnoea

53
Q
A

T

54
Q
A

100mg/12hr intitial
increase by 200mg every 2weeks
up to a max 1000mg

55
Q
A

IF MONOTHERAPY:
initial 25mg/d
increase by 50mg every 2 weeks
Max 250mg

56
Q
A

Sodium valproate

57
Q
A

Carbamazepine

phenytoin

58
Q
A

initial 300mg/12hrs

increase by 100mg/12hrs every 3 days

59
Q
A

carbamazepine
phenytoin
barbituates

60
Q
A
VALPROATE
appetite increase
Liver failure
Pancreatitis
reversible hair loss
Oedema
Ataxia
Teratogenic, thrombocytopenia, Tremor
Encephalopathy
Nausea
61
Q
A

Leucopenic
vision problems (diplopia/blurred)
Impaired balance

62
Q
A

Maculopapular rash
Stevens-johnsons syndrome (0.1%)
visual problems

63
Q
A
reduced IQ
depression
coarse facial features
visual problems
dysarthria
64
Q
A

lamotrigine for general

Carbamazepine for partial

65
Q
A

folic acid

66
Q
A

seizure free for > 2years
normal EEG
normal CNS exam
other (e.g. the need to drive)

67
Q
A

alcohol

benzodiazapines

68
Q
A

hippocampus

69
Q
A

sensory loss

motor (spread to precentral gyrus)