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NEUROLOGY > [Motor neurone disease] > Flashcards

[Motor neurone disease] Flashcards

1
Q
A

motor cortex
CN nuclei
anterior horn cells

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2
Q
A

normal function

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3
Q
A

none

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4
Q
A

NONE whatsoever

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5
Q
A

Amyotrophic lateral sclerosis
Progressive bulbar palsy
Progressive muscular atrophy
primary lateral sclerosis

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6
Q
A

motor cortex neurone damage
+
anterior horn cell damage

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7
Q
A

Both

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8
Q
A

9-12 CNs

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9
Q
A

anterior horn cells only (LMNL)

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10
Q
A

loss of Betz cells in motor cortex

UMNL

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11
Q
A

spastic gait
foot drop
weak grip
aspiration pneumonia

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12
Q
A

2-4 years

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13
Q
A

60 years

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14
Q
A

Riluzole

antiglutamatergic

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15
Q
A

Propantheline

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16
Q
A

LMNL

of 9-12 CNs

17
Q
A

UMNL

pf swallowing/talking muscle groups

18
Q
A

wasting of tongue
fasciculations of tongue
absent or normal jaw jerk

19
Q
A

increased jaw jerk
slow deliberate speech
emotional incontinence without emotional change

20
Q
21
Q
A

corticobulbar tracts

22
Q
A

El Escorial

23
Q
A 
Definite ALS
probable ALS
probably with lab support (EMG)
possible ALS
Suspected
24
Q
A

LMNL+UMNL signs in 3 regions

25
Q
A

LMNL+UMNL signs in 2 regions

26
Q
A

LMNL+UMNL signs in 1 regions

27
Q
A

UMNL or LMNL in 1 or more regions

28
Q
A

excess glutamate in MND
Na+ channel blocker
inhibits glutamate release

NEUROLOGY (29 decks)

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