[dementia] Flashcards
AMTS (abbreviated mental test score)
TYM (test your memory)
Alzheimers
Vascular dementia
Lewy body dementia
Fronto-temporal dementia (aka Pick’s)
vascular
Fluctuating cognitive impairment
Visual hallucinations
Parkinsonism
brainstem
neocortex (outermost layer of hemispheres)
Frontal
temporal
Ch.9
Episodic (autobiographical)
Picks
Trazodone(night)
Lorazepam
Lewy body
Downs syndrome
enduring global cognitive impairment (cf. certain domains affected only)
Visuo-spatial skill executive function anosognosia (lack of insight into problems caused by AD) Memory verbal ability
Accumulation of b-amyloid peptide
Acetylcholine neurotransmitter loss
amyloid plaques deposition
Neurofibrillary tangles
Hippocampus
amygdala
temporal neocortex
subcortical nuclei
loneliness (not just living alone)
vascular
B-amyloid changes in CSF
15
rivastigmine (Ach i)
they can exacerbate pre-existing heart block
Donepezil
Rivastigmine
Galantamine
Memantine (NMDA antagonist)
Solanezumab
B12
Folic acid
vascular
multiple small strokes
T
reduced thiamine
yes
Apolipoprotein E e4
CL1
CLU
PICALM
heart block
peptic ulcer
huge interplay between vasculopathy and AD
BP control
Acetylcholinesterase inhibitors