[parkinsonisms] Flashcards
Tremor
Rigidity/tone
Brady/hypokinesia
tremor at rest
pill-rolling
expressionless (hypomimesis)
decreased amplitude of movement
Neuroleptics
Metoclopramide (D-R antagonist)
Prochlorperazine (D-R2 antagonist)
Manganese
Copper (Wilson’s)
65
Mitochrondrial DNA dysfunction
degeneration of dopaminergic neurons in substantia nigra pars compacta
(associated with Lewy bodies)
5-10 years
Ropinirole
Pramipexole
[PD]: For sudden ‘off’ freezing, what medical Tx (in ‘rescue-pen’ form) is used?
Apomorphine
reduced sense of smell
constipation
depression
poor emotional content of speech decoding
Freezing whilst walking
Selegiline
Rasagiline
COMT inhibitors
(entacapone/tolcapone)
hepatic complications
(LFTs monitor)
Benzhexol
Orphenadrine
(anticholinergics)
Confusion in elderly
Carbidopa
(madopar/Sinemet)
Disease progression
Drug SE
Domperidone