[parkinsonisms] Flashcards

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1
Q
A

Tremor
Rigidity/tone
Brady/hypokinesia

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2
Q
A

tremor at rest

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3
Q
A

pill-rolling

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4
Q
A

expressionless (hypomimesis)

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5
Q
A

decreased amplitude of movement

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6
Q
A

Neuroleptics

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7
Q
A

Metoclopramide (D-R antagonist)
Prochlorperazine (D-R2 antagonist)

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8
Q
A

Manganese
Copper (Wilson’s)

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9
Q
A

65

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10
Q
A

Mitochrondrial DNA dysfunction
degeneration of dopaminergic neurons in substantia nigra pars compacta
(associated with Lewy bodies)

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11
Q
A

5-10 years

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12
Q
A

Ropinirole
Pramipexole

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13
Q

[PD]: For sudden ‘off’ freezing, what medical Tx (in ‘rescue-pen’ form) is used?

A

Apomorphine

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14
Q
A

reduced sense of smell
constipation
depression

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15
Q
A

poor emotional content of speech decoding

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16
Q
A

Freezing whilst walking

17
Q
A

Selegiline
Rasagiline

18
Q
A

COMT inhibitors
(entacapone/tolcapone)

19
Q
A

hepatic complications
(LFTs monitor)

20
Q
A

Benzhexol
Orphenadrine
(anticholinergics)

21
Q
A

Confusion in elderly

22
Q
A

Carbidopa
(madopar/Sinemet)

23
Q
A

Disease progression
Drug SE

24
Q
A

Domperidone

25
Q
A

VIVID

26
Q
A

progressive supra nuclear palsy

27
Q
A

Multi system atrophy

28
Q
A

Lewy body dementia

29
Q
A

Cortico-basal degeneration

30
Q
A

Vascular parkinsons

31
Q
A

partly dopamine responsive

32
Q
A

Ablation of sub-thalamic nucleus